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Quizzes and Polls

Latest Quiz

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August 2016

A Young Man With Recurrent Coma and Refractory Status Epilepticus

A man in his 30s presented with a 5-day history of vomiting, followed by lethargy and confusion. Two years prior, he had been hospitalized with coma with no identifiable precipitant. What is your diagnosis?

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Test your knowledge with previous versions of the JAMA Neurology Clinical Challenge.

June 2016

Worsening Stroke Symptoms in an 80-Year-Old Man

An 80-year-old man presented to the hospital with new-onset slurred speech and left-sided facial droop. Magnetic resonance imaging scans of the head were visually interpreted to show an acute infarct involving the posterior right frontal lobe. What is your diagnosis?

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April 2016

Keeping an Eye on This Headache

A 24-year-old woman had a strong unilateral headache located in her left cheek, eye, and forehead that evolved during the evening hours, peaked at night, and decreased again until the morning, without any remarkable trigger along with ipsilateral lacrimation, a red eye, and periorbital swelling but without ptosis. What is your diagnosis?

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January 2016

Primary Leptomeningeal Lymphoma

A 69-year-old white man presented to the emergency department reporting 2 months of progressive bilateral lower extremity weakness, left facial weakness, and diplopia in the setting of a 20.4-kg weight loss over the previous 6 months and new onset urinary incontinence. What is your diagnosis?

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November 2015

Acute-Onset Sleepiness and Decrease in Consciousness

A woman in her 30s presented with acute-onset sleepiness and decrease in consciousness, no history of neurologic disease or substance use, and laboratory findings within reference ranges. What is your diagnosis?

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September 2015

Subacute Imbalance in a Renal Transplant Patient

A woman in her 50s presented with a 1-month history of gait unsteadiness and imbalance, suspected to be due to neuropathy, but she then returned to the emergency department with 2 successive transient episodes, each lasting less than 1 hour, of acute dizziness, disorientation, gait dysfunction, and confusion. What is your diagnosis?

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March 2015

Personality Change and Gait Dysfunction

A woman in her 50s was referred to a neurologist for a history of gait, balance, personality, and judgment changes over 4 years.

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July 2014

July 2014

A 48-year-old woman was brought to the local hospital emergency department because of a month-long history of increasing depression, insomnia, anorexia, and weight loss and a 2-week lack of speech communication.

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April 2014

An 87-year-old woman arrived at the emergency department after she fell at home, where she lived with a relative. The family noted that she had a 2-year history of mild dementia for which she had been prescribed donepezil hydrochloride and a 5-week history of progressive gait impairment requiring a cane and then a walker.

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January 2014

A 69-year-old woman presented with several weeks of headache, neck pain, nausea, photophobia, and bilateral upper extremity tremor, was admitted to a hospital, and then developed over a day burning dysesthesias on the right torso and rapidly progressive right arm and right leg weakness.

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October 2013

A 55-year-old woman presented with a 2-week history of low-grade fever and holocephalic headache, which mostly resolved but were followed by a 2-week history of increasing dizziness, imbalance, and falls as well as gradual subtle mental confusion.

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July 2013

A 55-year-old woman presented with a 2-week history of low-grade fever and holocephalic headache, which mostly resolved but were followed by a 2-week history of increasing dizziness, imbalance, and falls as well as gradual subtle mental confusion.

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April 2013

A 65-year-old man presented to his local emergency department after noticing that he was staggering and had slurred speech for much of the day.

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January 2013

A 53-year-old man with diabetes mellitus, hypertension, coronary artery disease, prior myocardial infarction, and alcohol use presented with vertigo, ataxia, headaches, and panic attacks.

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October 2012

A 34-year-old man with no prior medical or neurological difficulties presented with a 4-month history of progressive behavioral change, short-term memory loss, fatigue, and weight loss.

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July 2012

An 83-year-old man presented with progressive increasing lethargy, gait impairment, imbalance, increased tremors, and urinary incontinence evolving over 2 months. Previously, he was fully functional and carrying out activities independently, although he had a minor tremor of the left fingers for 30 years and a mild shuffling gait for 4 years.

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April 2012

A 40-year-old right-handed man previously functioning well at a high-level occupation presented with a 2-year history of increasing drug and alcohol abuse leading to attendance at multiple rehabilitation programs, which, however, was unsuccessful.

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January 2012

An 84-year-old, right-handed, independent, community-dwelling woman with a history of hypertension, hyperlipidemia, angina, and asthma was in her usual good health until noted one afternoon by a neighbor to have slowness of conversation without other evident problems.

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October 2011

A 32-year-old right-handed man with a history of AIDS presented with a series of 3 generalized epileptic seizures, associated with lip laceration, incontinence, postictal sonorous breathing, and postictal lethargy.

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July 2011

A 55-year-old right-handed man with a history of quiescent seizure disorder presented with recurrent repetitive seizures.

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April 2011

A 60-year-old woman presented with a 10-year history of gradually deteriorating cognitive and then motor dysfunction.

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January 2011

A 71-year-old woman presented with a history of increasing memory problems for 4 months.

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