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Original Contribution | October 8, 2012 
Using Exome Sequencing to Reveal Mutations in TREM2 Presenting as a Frontotemporal Dementia–like Syndrome Without Bone Involvement
Rita João Guerreiro, PhD; Ebba Lohmann, MD; José Miguel Brás, PhD; Jesse Raphael Gibbs, MS; Jonathan D. Rohrer, MRCP; Nicole Gurunlian, MS; Burcu Dursun, MD; Basar Bilgic, MD; Hasmet Hanagasi, MD; Hakan Gurvit, MD; Murat Emre, MD; Andrew Singleton, PhD; John Hardy, PhD
Includes: Supplemental Content
ObjectiveObjective To identify new genes and risk factors associated with frontotemporal dementia (FTD). Several genes and loci have been associated with different ...
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Arch Neurol. Published online October 08, 2012. doi:10.1001/archneurol.2013.579
Original Contribution | October 8, 2012 
Differences in Brain Activation Between Tremor- and Nontremor-Dominant Parkinson Disease
Janey Prodoehl, PhD; Peggy J. Planetta, PhD; Ajay S. Kurani, MS; Cynthia L. Comella, MD; Daniel M. Corcos, PhD; David E. Vaillancourt, PhD
ObjectiveObjective To compare differences in functional brain activity between tremor- and nontremor-dominant subtypes of Parkinson disease (PD) using functional magnetic resonance imaging.DesignDesign ...
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Arch Neurol. Published online October 08, 2012. doi:10.1001/archneurol.2013.582
Editorial | October 1, 2012 
Getting Beyond the Ganglion Cell:  Morphometric Adjustments for Retinal Optical Coherence Tomography in Multiple Sclerosis
Ari J. Green, MD, MCR
The treatment of relapsing multiple sclerosis (MS) remains a rare beacon of success in the long campaign against neurological disease. The ready ...
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Arch Neurol. Published online October 01, 2012. doi:10.1001/archneurol.2013.430
Neurological Review | October 1, 2012 
F-Box Only Protein 7 Gene in Parkinsonian-Pyramidal Disease
Hao Deng, MD, PhD; Hui Liang, MD; Joseph Jankovic, MD
Parkinson disease is one of the most common neurodegenerative diseases associated with aging. At least 18 genetic loci and 13 disease-related genes ...
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Arch Neurol. Published online October 01, 2012. doi:10.1001/archneurol.2013.572
Original Contribution | October 1, 2012 
Relationships Between Retinal Axonal and Neuronal Measures and Global Central Nervous System Pathology in Multiple Sclerosis
Shiv Saidha, MBBCh, MRCPI; Elias S. Sotirchos, MD; Jiwon Oh, MD, FRCPC; Stephanie B. Syc, ScB; Michaela A. Seigo, ScB; Navid Shiee, MS; Chistopher Eckstein, MD; Mary K. Durbin, PhD; Jonathan D. Oakley, PhD; Scott A. Meyer, PhD; Teresa C. Frohman, BS; Scott Newsome, DO; John N. Ratchford, MD; Laura J. Balcer, MD, MSCE; Dzung L. Pham, PhD; Ciprian M. Crainiceanu, PhD; Elliot M. Frohman, MD, PhD; Daniel S. Reich, MD, PhD; Peter A. Calabresi, MD
Includes: Supplemental Content
ObjectiveObjective To determine the relationships between conventional and segmentation-derived optical coherence tomography (OCT) retinal layer thickness measures with intracranial volume (a surrogate ...
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Arch Neurol. Published online October 01, 2012. doi:10.1001/archneurol.2013.573
Observation | October 1, 2012 
Intracranial Aneurysm and Recessive Polycystic Kidney Disease:  The Third Reported Case
Viviane Chalhoub, MD; Lise Abi-Rafeh, MD; Kamal Hachem, MD; Eliane Ayoub, MD; Patricia Yazbeck, MD
ObjectiveObjective To highlight the possible association of intracranial aneurysm with autosomal recessive polycystic kidney disease.Design, Setting, and PatientDesign, Setting, and Patient To ...
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Arch Neurol. Published online October 01, 2012. doi:10.1001/archneurol.2013.584
Original Contribution | September 24, 2012 
Differential Diagnosis of Jakob-Creutzfeldt Disease
Ross W. Paterson, MRCP; Charles C. Torres-Chae, MPA; Amy L. Kuo, MS, RN, GNP; Tim Ando, BA; Elizabeth A. Nguyen, BS; Katherine Wong, BS; Stephen J. DeArmond, MD, PhD; Aissa Haman, MD; Paul Garcia, MD; David Y. Johnson; Bruce L. Miller, MD; Michael D. Geschwind, MD, PhD
ObjectivesObjectives To identify the misdiagnoses of patients with sporadic Jakob-Creutzfeldt disease (sCJD) during the course of their disease and determine which medical ...
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Arch Neurol. Published online September 24, 2012. doi:10.1001/archneurol.2013.79
Original Contribution | September 10, 2012 
β-Amyloid Dynamics in Human Plasma
Yafei Huang, PhD; Rachel Potter, BA; Wendy Sigurdson, MSN; Tom Kasten, PhD; Rose Connors, BA; John C. Morris, MD; Tammie Benzinger, MD; Mark Mintun, MD; Tim Ashwood, PhD; Mats Ferm, PhD; Samantha L. Budd, PhD; Randall J. Bateman, MD
Includes: Supplemental Content
ObjectivesObjectives To investigate dynamic changes in human plasma β-amyloid (Aβ) concentrations, evaluate the effects of aging and amyloidosis on these dynamics, and ...
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Arch Neurol. Published online September 10, 2012. doi:10.1001/archneurol.2012.1810

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