Mutations in SNCA, LRRK2, VPS35, EIF4G1, and DNAJC13 have been implicated in late-onset familial parkinsonism. However, the estimated disease penetrance of these mutations varies widely.
To compare penetrance of various mutations reported in published genetic studies to improve the understanding of late-onset parkinsonism....
JAMA Neurol. Published online October 20, 2014. doi:10.1001/jamaneurol.2014.1909