July 28, 2014
Intranetwork and Internetwork Default Mode Functional Connectivity
A fitted model predicts that whole-brain intranetwork (warm colors) and internetwork (cool colors) default mode functional connectivity declines with estimated years from symptom onset in M+ individuals (n = 57) and begins to disappear approximately at the anticipated age at symptom onset.
JAMA Neurol. Published online July 28, 2014.;():. doi:10.1001/jamaneurol.2014.1654.
Jewell B. Thomas, BA; Matthew R. Brier, BS; Randall J. Bateman, MD; Abraham Z. Snyder, MD, PhD; Tammie L. Benzinger, MD, PhD; Chengjie Xiong, PhD; Marcus Raichle, MD; David M. Holtzman, MD; Reisa A. Sperling, MD; Richard Mayeux, MD; Bernardino Ghetti, MD; John M. Ringman, MD; Stephen Salloway, MD; Eric McDade, DO; Martin N. Rossor, MD; Sebastien Ourselin, PhD; Peter R. Schofield, PhD; Colin L. Masters, MD; Ralph N. Martins, PhD; Michael W. Weiner, MD; Paul M. Thompson, PhD; Nick C. Fox, MD; Robert A. Koeppe, PhD; Clifford R. Jack, Jr, MD; Chester A. Mathis, PhD; Angela Oliver, RN; Tyler M. Blazey, BS; Krista Moulder, PhD; Virginia Buckles, PhD; Russ Hornbeck, MS; Jasmeer Chhatwal, MD, PhD; Aaron P. Schultz, PhD; Alison M. Goate, DPhil; Anne M. Fagan, PhD; Nigel J. Cairns, PhD; Daniel S. Marcus, PhD; John C. Morris, MD; Beau M. Ances, MD, PhD