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Original Investigation | May 18, 2015 FREE ONLINE FIRST

IL-6 Receptor Blockade in Highly Active Neuromyelitis Optica Spectrum Disorder

This cohort study evaluates the long-term safety and efficacy of tocilizumab, a humanized antibody targeting the interleukin 6 receptor, in 8 female patients with neuromyelitis optica (NMO) and NMO spectrum disorder.
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Original Investigation | May 18, 2015 ONLINE FIRST

Memory and Concussion History in Retired National Football League Athletes

This cross-sectional study compares associations between hippocampal volume, memory performance, and concussion history among retired National Football League athletes with and without mild cognitive impairment.

Original Investigation | May 11, 2015 FREE ONLINE FIRST

Genetic Variants Associated With Risk of Ischemic Stroke

This genome-wide association study identifies 2 novel genes, PDE4DIP and ACOT4, that are associated with an increased risk for ischemic stroke.

Clinical Implications of Basic Neuroscience Research | May 11, 2015 ONLINE FIRST

Neuroelectronics and Biooptics

This article discusses how advances in experimental closed-loop systems hold promise for improved clinical benefit in patients with neurological disorders.

Images in Neurology | May 11, 2015 ONLINE FIRST  audio icon

Eight-and-a-Half Syndrome

This case report describes a patient with an ischemic pontine infarct presenting as left internuclear ophthalmoplegia and horizontal left-sided gaze palsy accompanied by left-sided peripheral facial palsy.

Explore more articles:  Current Issue | Online First

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Author Interview

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Interview with Douglas A. Dulli, MD, MS, author of In-Hospital Stroke: Hidden in Plain Sight, and Moira K. Kapral, MD, MSc, author of Care and Outcomes of Patients With In-Hospital Stroke

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Care and Outcomes of Patients With In-Hospital Stroke

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Video Recording of the Patient (01:28)

The video shows the patient’s ophthalmoplegia and facial palsy.


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Latest Quiz

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Personality Change and Gait Dysfunction

A woman in her 50s was referred to a neurologist for a history of gait, balance, personality, and judgment changes over 4 years.

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American Neurological Association Satellite Symposium

The American Neurological Association is having a satellite symposium “Circuits and Circuit Disorders: Approaches to Neuromodulation,” Saturday, September 26, 2015, 7:00 pm, Marriott Downtown Hotel, Chicago, Illinois, the evening before the start of the annual meeting. It is cosponsored by the Annals of Neurology and JAMA Neurology and features Mahlon Delong, MD, Emory University, 2014 Lasker Prize in Medicine recipient for his research in developing deep brain stimulation; Philip Starr, MD, PhD, University of California, San Francisco, the dystonias; Jonathan Mink, MD, PhD, University of Rochester Medical Center, Tourette syndrome; Helen Mayberg, MD, Emory University, depression; and Bryan L. Roth, PhD, University of North Carolina, chemogenetics.

Registration for the meeting and hotel accommodations can be obtained at http://myana.org/events/ana-2015-annual-meeting.

Call for Papers

We are asking for papers to be submitted on the subject of Neuromodulation to appear in a theme issue on Neuromodulation to be published at the time of the American Neurological Association Satellite Symposium on “Circuits and Circuit Disorders: Approaches to Neuromodulation” on September 26, 2015, cosponsored by the Annals of Neurology and JAMA Neurology, at the 140th Annual Meeting of the American Neurological Association in Chicago, Illinois, at the Marriott Downtown Hotel. Articles on deep brain stimulation related to movement disorders, Tourette syndrome, obsessive-compulsive disease, depression, chemogenetics, and related disorders will be considered.

Articles must be received by May 1, 2015, to allow time for peer review and necessary revisions, so that they may appear online in JAMA Neurology in September.

Annual Meeting: American Neurological Association

Announcing the American Neurological Association’s 140th annual meeting, Chicago, Illinois, September 27-29, 2015.

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