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Published monthly, JAMA Neurology brings you an international perspective on a wide range of topics from the leading centers of neurological research. Subscribe/Learn More

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Original Investigation | September 26, 2016 ONLINE FIRST

Efficacy and Safety of Rituximab in Neuromyelitis Optica Spectrum Disorders

This systematic review and meta-analysis evaluates the efficacy and safety of rituximab therapy in neuromyelitis optica spectrum disorders, considering the potential predictive factors related to patient response to rituximab in this disease.

Original Investigation | September 19, 2016 FREE ONLINE FIRST

Neurochemical Aftermath of Mild Traumatic Brain Injury

This study investigates whether persistent symptoms after mTBI are associated with brain injury as evaluated by cerebrospinal fluid biochemical markers for axonal damage and other aspects of central nervous system injury.

Original Investigation | September 12, 2016 ONLINE FIRST

Endovascular Therapy for Acute Ischemic Stroke

This pooled cohort study evaluates the safety and effectiveness of endovascular therapy for occlusions of the M2 segment of the middle cerebral artery in patients with ischemic stroke.

Original Investigation | September 6, 2016 ONLINE FIRST

Preclinical Assessment of Young Plasma for Alzheimer Disease

This preclinical study determines whether young blood plasma ameliorates pathology and cognition in a mouse model for AD.

Original Investigation | August 29, 2016 ONLINE FIRST

GBA Mutations and the E326K Polymorphism in Parkinson Disease

This cohort study examines the association of GBA mutations and E326K polymorphisms with progression of motor symptoms and cognitive decline in patients with Parkinson disease.

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Interview with Vanda A. Lennon, MD, PhD, author of Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy: A Novel Meningoencephalomyelitis, and Robert P. Lisak, MD, author of Expanding the Range of Diagnosable Autoimmune Encephalopathies and Encephalomyelopathies

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Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy A Novel Meningoencephalomyelitis

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Episodic Dystonia (0:24)

Video EEG recording showing a typical event consisting of a rapid dystonia involving the right arm and associated with the patient’s described cycling auras.

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A Young Man With Recurrent Coma and Refractory Status Epilepticus

A man in his 30s presented with a 5-day history of vomiting, followed by lethargy and confusion. Two years prior, he had been hospitalized with coma with no identifiable precipitant.

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