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Published monthly, JAMA Neurology brings you an international perspective on a wide range of topics from the leading centers of neurological research. Subscribe/Learn More

In the Media
Dietary ω-3 Polyunsaturated Fatty Acid Intake and Risk for Amyotrophic Lateral Sclerosis. Fitzgerald et al.

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Association of Lifetime Intellectual Enrichment With Cognitive Decline in the Older Population. Vemuri et al.

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Hemorrhage After Tissue Plasminogen Activator

Yaghi et al provide an overview on the rationale and mechanism of action of potential treatments for symptomatic intracerebral hemorrhage that may reverse the coagulopathy before hematoma expansion occurs after intravenous recombinant tissue plasminogen activator is administered.

Serial MRI Changes in Creutzfeldt-Jakob Disease

This case report illustrates serial MRI changes in a patient with sporadic Creutzfeldt-Jakob disease with valine homozygosity at codon 129 of the prion protein gene.

Moral Judgments of Patients With Frontotemporal Dementia and Frontal Stroke

This cross-sectional study compared the moral judgments of patients with frontotemporal dementia and frontal stroke using a task designed to distinguish intentions from outcomes.

Thrombolysis Times in Acute Ischemic Stroke

Sauser et al examine the contributions of door-to-imaging time and imaging-to-needle time to delays in delivery of tissue plasminogen activator to patients with acute ischemic stroke.

Dietary Polyunsaturated Fatty Acid Intake and Risk for ALS

Fitzgerald and colleagues examined the association between ω-6 and ω-3 polyunsaturated fatty acid (PUFA) consumption and the risk for amyotrophic lateral sclerosis (ALS).
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Interview with Neal E. Little, MD, author of Therapeutic Hypothermia After Cardiac Arrest Without Return of Consciousness: Skating on Thin Ice

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Therapeutic Hypothermia After Cardiac Arrest Without Return of Consciousness:  Skating on Thin Ice

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Intranetwork and Internetwork Default Mode Functional Connectivity (01:24)

A fitted model predicts that whole-brain intranetwork (warm colors) and internetwork (cool colors) default mode functional connectivity declines with estimated years from symptom onset in M+ individuals (n = 57) and begins to disappear approximately at the anticipated age at symptom onset.


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What is your diagnosis?

A 48-year-old woman was brought to the local hospital emergency department because of a month-long history of increasing depression, insomnia, anorexia, and weight loss and a 2-week lack of speech communication.

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Annual Meeting: American Neurological Association

Announcing the American Neurological Association annual meeting, Baltimore, Maryland, October 12-14, 2014

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Author Saurav Chatterjee, MD, discusses Oral Anticoagulants and Intracranial Hemorrhage.

Author Lorina Naci, PhD, discusses Making Every Word Count for Nonresponsive Patients.

Author Gil Rabinovici, MD, discusses Progranulin Mutations as Risk Factors for Alzheimer Disease.

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