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Published monthly, JAMA Neurology brings you an international perspective on a wide range of topics from the leading centers of neurological research. Subscribe/Learn More

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Original Investigation | August 22, 2016 FREE ONLINE FIRST

Tau Deposition and Cognitive Decline in Patients With Non-Alzheimer Pathophysiology

This cohort study assesses PET-measured tau deposition and cognitive decline over 5 years in Harvard Aging Brain study participants who were beta-amyloid-negative with neurodegeneration at baseline.

Original Investigation | August 15, 2016 ONLINE FIRST

Association Between CV Risk Factors and Familial Alzheimer Disease

This cohort study investigates associations between coronary risk factors, stroke, and late-onset Alzheimer dementia in patients with familial disease.

Original Investigation | August 8, 2016 ONLINE FIRST

Serum Docosahexaenoic Acid and Cerebral Amyloidosis

This cross-sectional study investigates correlations between serum DHA levels and cerebral amyloidosis, brain volumes, and neuropsychological testing measures in Aging Brain Study participants.

Clinical Implications of Basic Neuroscience Research | August 1, 2016 ONLINE FIRST

Antisense Oligonucleotide Treatment of Neurological Disease

This narrative review summarizes the evolution of antisense oligonucleotides for treatment of neurological disorders.

Original Investigation | July 25, 2016 ONLINE FIRST

Tau Imaging in Staging Alzheimer Disease

This study characterizes the diagnostic accuracy of [18F]-AV-1451 PET imaging for detecting in vivo tau protein in patients with Alzheimer disease.

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Interview with Paul K. Crane, MD, MPH, author of Association of Traumatic Brain Injury With Late-Life Neurodegenerative Conditions and Neuropathologic Findings

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Association of Traumatic Brain Injury With Late-Life Neurodegenerative Conditions and Neuropathologic Findings

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Episodic Dystonia (0:24)

Video EEG recording showing a typical event consisting of a rapid dystonia involving the right arm and associated with the patient’s described cycling auras.

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A Young Man With Recurrent Coma and Refractory Status Epilepticus

A man in his 30s presented with a 5-day history of vomiting, followed by lethargy and confusion. Two years prior, he had been hospitalized with coma with no identifiable precipitant.

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