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This case-control study of older patients with enlarged Virchow-Robin spaces throughout the striatum (Swiss cheese striatum) reports no association with development of extrapyramidal clinical disorders.
Lu and colleagues summarize current knowledge about IgG4-related hypertrophic pachymeningitis, including its pathological, clinical, and radiological presentations.
This Clinical Pathologic Conference discuss the differential diagnosis of a 42-year-old man with cognitive impairment, behavioral changes, rapidly progressive motor and gait impairment, and MRI abnormalities.
This cohort study used participants in Parkinson disease treatment trials to identify measures of functional status and quality of life associated with disease progression.
Hughes et al examine the association between measures of arterial stiffness and change in cerebral β-amyloid deposition over time.
Interview with Eugene O. Major, PhD, author of JC Virus in CD34+ and CD19+ Cells in Patients With Multiple Sclerosis Treated With Natalizumab
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The 65-Year-Old Woman With Ataxia
The patient demonstrated scanning speech, dysmetria in the finger-nose test, slow and irregular rapid alternating movements, and irregular knee-shin slides.
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An 87-year-old woman arrived at the emergency department after she fell at home, where she lived with a relative. The family noted that she had a 2-year history of mild dementia for which she had been prescribed donepezil hydrochloride and a 5-week history of progressive gait impairment requiring a cane and then a walker.
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Announcing the American Academy of Neurology annual meeting, Philadelphia, Pennsylvania, April 26 - May 3, 2014.
International translations of Author Video Interviews
Author Saurav Chatterjee, MD, discusses Oral Anticoagulants and Intracranial Hemorrhage.
Author Lorina Naci, PhD, discusses Making Every Word Count for Nonresponsive Patients.
Author Gil Rabinovici, MD, discusses Progranulin Mutations as Risk Factors for Alzheimer Disease.
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