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Published monthly, JAMA Neurology brings you an international perspective on a wide range of topics from the leading centers of neurological research. Subscribe/Learn More

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Original Investigation | July 25, 2016 FREE ONLINE FIRST

Tau Imaging in Staging Alzheimer Disease

This study characterizes the diagnostic accuracy of [18F]-AV-1451 PET imaging for detecting in vivo tau protein in patients with Alzheimer disease.
Editorial

Original Investigation | July 18, 2016 ONLINE FIRST

Autoimmune Encephalitis With Anti-CASPR2 CSF Antibodies

This case series describes the clinical and radiographic characteristics of patients with anti–contactin-associated protein-like 2 (CASPR2) antibodies in their cerebrospinal fluid.
Editorial

Original Investigation | July 11, 2016 ONLINE FIRST  audio icon

Association of TBI and Late-Life Neurodegenerative Conditions

This study uses data pooled from 3 cohort studies to assess associations between traumatic brain injury with loss of consciousness and risk for clinical and neuropathologic findings of Alzheimer disease, Parkinson disease, and other dementias in US adults.

Original Investigation | July 5, 2016 ONLINE FIRST

Safety and Efficacy of Siponimod in Relapsing-Remitting Multiple Sclerosis

This study reports outcomes up to 24 months from a trial that compared the safety and efficacy of siponimod, a sphingosine 1-phosphate receptor modulator, at different doses in patients with relapsing-remitting multiple sclerosis.
Editorial

Original Investigation | June 27, 2016 ONLINE FIRST

Times and Regions of Birth Effects in Multiple Sclerosis

This study examines data on the season and region of birth in individuals in the United Kingdom who develop multiple sclerosis.
Editorial

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Interview with Paul K. Crane, MD, MPH, author of Association of Traumatic Brain Injury With Late-Life Neurodegenerative Conditions and Neuropathologic Findings

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Association of Traumatic Brain Injury With Late-Life Neurodegenerative Conditions and Neuropathologic Findings

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Episodic Dystonia (0:24)

Video EEG recording showing a typical event consisting of a rapid dystonia involving the right arm and associated with the patient’s described cycling auras.


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Worsening Stroke Symptoms in an 80-Year-Old Man

An 80-year-old man presented to the hospital with new-onset slurred speech and left-sided facial droop. Magnetic resonance imaging scans of the head were visually interpreted to show an acute infarct involving the posterior right frontal lobe.

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