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Published monthly, JAMA Neurology brings you an international perspective on a wide range of topics from the leading centers of neurological research. Subscribe/Learn More

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Amyotrophic Lateral Sclerosis Outcome Measures and the Role of Albumin and Creatinine: A Population-Based Study. Chio et al.

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Dietary ω-3 Polyunsaturated Fatty Acid Intake and Risk for Amyotrophic Lateral Sclerosis. Fitzgerald et al.

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Exome Sequencing For Diagnosing Cerebellar Ataxia

This case series describes the diagnostic yield of exome sequencing in patients with chronic progressive cerebellar ataxia.
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Episodic Bradycardia

This case series describes 14 patients with VGKCc/LGI1-Ab (voltage-gated potassium channel complex antibody/leucine-glioma rich inactivated 1) encephalitis in whom episodic bradycardia severe enough to require pacemaker implantation preceded the onset of encephalopathy.

Impaired Cerebrovascular Reactivity in MS

Marshall and coauthors use hypercapnic perfusion magnetic resonance imaging to assess cerebrovascular reactivity impairment in patients with multiple sclerosis.

Effects of the Absence of Apolipoprotein E

This case report describes the clinical and genetic characteristics of a patient with complete absence of apolipoprotein E.
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Triheptanoin in Glucose Transporter Type I Deficiency

Pascual et al evaluate the use of triheptanoin in the treatment of glucose transporter type I deficiency in a case series including 14 patients.

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Interview with Neal E. Little, MD, author of Therapeutic Hypothermia After Cardiac Arrest Without Return of Consciousness: Skating on Thin Ice

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Therapeutic Hypothermia After Cardiac Arrest Without Return of Consciousness:  Skating on Thin Ice

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Intranetwork and Internetwork Default Mode Functional Connectivity (01:24)

A fitted model predicts that whole-brain intranetwork (warm colors) and internetwork (cool colors) default mode functional connectivity declines with estimated years from symptom onset in M+ individuals (n = 57) and begins to disappear approximately at the anticipated age at symptom onset.


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What is your diagnosis?

A 48-year-old woman was brought to the local hospital emergency department because of a month-long history of increasing depression, insomnia, anorexia, and weight loss and a 2-week lack of speech communication.

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Annual Meeting: American Neurological Association

Announcing the American Neurological Association annual meeting, Baltimore, Maryland, October 12-14, 2014

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Introducing JAMA Network Author Video Interviews

Author Saurav Chatterjee, MD, discusses Oral Anticoagulants and Intracranial Hemorrhage.

Author Lorina Naci, PhD, discusses Making Every Word Count for Nonresponsive Patients.

Author Gil Rabinovici, MD, discusses Progranulin Mutations as Risk Factors for Alzheimer Disease.

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