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April 2014
Vol 71, No. 4
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Published monthly, JAMA Neurology brings you an international perspective on a wide range of topics from the leading centers of neurological research. Subscribe/Learn More

In the Media
Arterial Stiffness and β-Amyloid Progression in Nondemented Elderly Adults. Hughes et al

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Philadelphia Inquirer
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Monthly Prescribing Reference

JC Virus in CD34+ and CD19+ Cells in Patients With Multiple Sclerosis Treated With Natalizumab. Frohman et al

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Philadelphia Inquirer

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Swiss Cheese Striatum

This case-control study of older patients with enlarged Virchow-Robin spaces throughout the striatum (Swiss cheese striatum) reports no association with development of extrapyramidal clinical disorders.

IgG4-Related Hypertrophic Pachymeningitis

Lu and colleagues summarize current knowledge about IgG4-related hypertrophic pachymeningitis, including its pathological, clinical, and radiological presentations.

Progressive Neuropsychiatric Symptoms

This Clinical Pathologic Conference discuss the differential diagnosis of a 42-year-old man with cognitive impairment, behavioral changes, rapidly progressive motor and gait impairment, and MRI abnormalities.

Measuring Disease Progression in Early Parkinson Disease

This cohort study used participants in Parkinson disease treatment trials to identify measures of functional status and quality of life associated with disease progression.

Arterial Stiffness and β-Amyloid Progression

Hughes et al examine the association between measures of arterial stiffness and change in cerebral β-amyloid deposition over time.

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Author Interview

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Interview with Eugene O. Major, PhD, author of JC Virus in CD34+ and CD19+ Cells in Patients With Multiple Sclerosis Treated With Natalizumab


JC Virus in CD34+ and CD19+ Cells in Patients With Multiple Sclerosis Treated With Natalizumab

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The 65-Year-Old Woman With Ataxia (01:52)

The patient demonstrated scanning speech, dysmetria in the finger-nose test, slow and irregular rapid alternating movements, and irregular knee-shin slides.

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What is your diagnosis?

An 87-year-old woman arrived at the emergency department after she fell at home, where she lived with a relative. The family noted that she had a 2-year history of mild dementia for which she had been prescribed donepezil hydrochloride and a 5-week history of progressive gait impairment requiring a cane and then a walker.

What is your diagnosis?

Annual Meeting: American Academy of Neurology

Announcing the American Academy of Neurology annual meeting, Philadelphia, Pennsylvania, April 26 - May 3, 2014.

Video Translations

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Introducing JAMA Network Author Video Interviews

Author Saurav Chatterjee, MD, discusses Oral Anticoagulants and Intracranial Hemorrhage.

Author Lorina Naci, PhD, discusses Making Every Word Count for Nonresponsive Patients.

Author Gil Rabinovici, MD, discusses Progranulin Mutations as Risk Factors for Alzheimer Disease.

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