TY - JOUR T1 - MEningococcal meningitis with brainstem infarction AU - van de Beek D, Patel R, Wijdicks EM Y1 - 2007/09/01 N1 - 10.1001/archneur.64.9.1350 JO - Archives of Neurology SP - 1350 EP - 1351 VL - 64 IS - 9 N2 - A 25-year-old woman was admitted with confusion, headache, and vomiting. Physical examination showed disorientation to time and place, difficulty following commands, and neck stiffness. Lumbar puncture revealed a cerebrospinal fluid (CSF) leukocyte count of 0.674/μL and a low CSF–blood glucose ratio. Ceftriaxone sodium administration was started empirically; CSF cultures grew Neisseria meningitidis. The second day, a sudden respiratory arrest occurred. No seizures were noted. Computed tomography revealed dilatation of the entire ventricular system, indicating communicating hydrocephalus (Figure). A right frontal external ventricular drain was placed for 5 days. The patient's confusion resolved after CSF drainage; however, a mild right hemiparesis and a right-sided Horner syndrome were noticed. Magnetic resonance imaging showed a focal zone of signal abnormality in the right dorsal aspect of the medulla oblongata, which had restricted diffusion, suggestive of cerebral infarction (Figure). Hemiparesis gradually improved over the course of hospitalization, but some numbness of the right hand remained. SN - 0003-9942 M3 - doi: 10.1001/archneur.64.9.1350 UR - http://dx.doi.org/10.1001/archneur.64.9.1350 ER -