TY - JOUR T1 - MYeloneuropathy and macrocytosis associated with nitrous oxide abuse AU - Blanco G, Peters HA Y1 - 1983/07/01 N1 - 10.1001/archneur.1983.04050070046009 JO - Archives of Neurology SP - 416 EP - 418 VL - 40 IS - 7 N2 - • After four months of excessive nitrous oxide (N2O) exposure, a dentist had myeloneuropathy with spastic paraparesis, Lhermitte's sign, sensory shading, loss of position and vibration sense, ataxia, and impotence. Macrocytosis, hypersegmented neutrophils, and a reduced vitamin B12 level were associated with normal findings on gastric analysis and Schilling test. Complete hematologic and neurologic recovery followed N2O avoidance and vitamin therapy for six months. SN - 0003-9942 M3 - doi: 10.1001/archneur.1983.04050070046009 UR - http://dx.doi.org/10.1001/archneur.1983.04050070046009 ER -