RT Journal
A1 Crane GE
T1 PSeudoparkinsonism and tardive dyskinesia
JF Archives of Neurology
JO Archives of Neurology
YR 1972
FD November 1
VO 27
IS 5
SP 426
OP 430
DO 10.1001/archneur.1972.00490170058008
UL http://dx.doi.org/10.1001/archneur.1972.00490170058008
AB The main goal of this study was to show that tardive dyskinesia is more likely to develop in patients with pseudoparkinsonian symptoms than in patients not exhibiting such manifestations. This hypothesis was supported by data from three independent studies: (1) observation of neurological changes in 55 schizophrenic patients taken off a regimen of neuroleptic drugs; (2) a study of the evolution of symptoms in 400 subjects on various drug regimens over a one-year period; and (3) a controlled investigation of the effects of gradual removal of neuroleptics in four samples of patients exhibiting a variety of druginduced side effects or no drug related neurological manifestations.