0
October 1963, Vol 9, No. 4 >
Article | October 1963

Localized Cooling in the Central Nervous System: Title and subTitle BreakPart II. Histopathological Results

YUJI MIYAZAKI, MD; FRANK R. ERVIN, MD; JEAN SIEGFRIED, MD; EDWARD P. RICHARDSON, MD; VERNON H. MARK, MD
[+] Author Affiliations

Submitted for publication April 26, 1963; accepted June 8.

Present Address: Department of Neurosurgery, Sapporo Medical College and Hospital, S1, W-16, Sapporo, Japan (Dr. Miyazaki).

This work was supported by Grant No. NB-03425 from the National Institutes of Health, a grant from the United Cerebral Palsy Association, and the Hall-Mercer Fund.


Arch Neurol. 1963;9(4):392-399. doi:10.1001/archneur.1963.00460100080009
Text Size: A A A
Published online
Article
References
Comments

Introduction  The recent progress in clinical stereotactic surgery has largely been the result of detailed human brain atlases, effective procedures for making discrete brain lesions, and improved lightweight accurate stereotactic machines. These advances rely on the correlation of neuroanatomical landmarks with the radiographic ventricular outline. The individual variations in human brains plus the necessity of translating ventriculothalamic measurements obtained from the cadaver to the living patient give less than perfect accuracy in placing a stereotactic lesion within the cerebral target area. This is particularly true when the target area lies in the thalamus of a patient with infantile choreoathetosis, since diffuse brain pathology often distorts the relation of the target area to ventricular landmarks. In this situation, the necessity of using neurophysiological guides is apparent. Stimulation, recording of evoked potentials, and the production of reversible brain lesions have been the three standard physiological guides used by stereotactic surgeons. Our group

REFERENCES

1 +
Balthasar, K.:  Gezielte Kalteshaden in der Grosshimmide der Katze , Deutsch Z Nervenheilk 176:173, 1957;.
2 +
Bielschowsky, M., and Valentin, B.:  Die histologischen Veränderungen in durchfrorenen Nervenstrecken , J Psychol Neurol (Leipzig) 29:133, 1922;.
3 +
Cooper, I. S.: Personal communication to the authors.
4 +
Cooper, I. S.:  A Cryogenic Method for Physiologic Inhibition and Production of Lesions in the Brain , J Neurosurg 19:853, 1962;.
5 +
Denny-Brown, D.; Adams, R. D.; Brenner, C.; and Doherty, M. M.:  The Pathology of Injury to Nerve Induced by Cold , J Neuropath Exp Neurol 4:305, 1945;.
6 +
Dondey, M.; Albe-Fessard, D.; and LeBeau, J.:  Refroidissement temporaire et localisé de structures cérébrales profondes: Resultats physiologiques preliminaires , Rev Neurol (Paris) 105:186, 1961;.
7 +
Fox, R. H.:  Local Cooling in Man , Brit Med Bull 17:14, 1961;.
8 +
Fuhrman, F. A., and Crismon, J. M.:  Studies on Gangrene Following Cold Injury: I. A Method for Producing Gangrene by Means of Controlled Injury by Cold , J Clin Invest 26:229, 1947;.
9 +
Hammel, H. T.:  Thermoregulatory Responses to Hypothalamic Cooling in Unanesthetized Dogs , Amer J Physiol 198:481, 1960;.
10 +
Hass, G. H., and Taylor, C. B.:  Quantitative Hypothermal Method for Production of Local Injury of Tissue , Arch Path 45:563, 1948;.
11 +
Klatzo, I.; Piraux, A.; and Laskowski, E. J.:  The Relationship Between Edema, Blood-Brain Barrier, and Tissue Element in a Local Brain Injury , J Neuropath Exp Neurol 17:548, 1958;.
12 +
Kreyberg, L., and Retness, P.:  La stase experimentale méthode pour la mettre en évidence au moyende préparations spéciales , CR Soc Biol (Paris) 106:895, 1931;.
13 +
Kulka, J. P., and Brigham, R. B.:  Circulatory Change in Cold Injury of the Mouse Ear: An Experimental Approach to the Pathogenesis of Vasospastic Tissue Damage , Amer J Path 35:705, 1959;.
14 +
Lewis, R. B.: Cold Injury , Bristol, Conn: Hildreth Press, Inc., 1952;, p 24.
15 +
Lovelock, J. E.:  The Denaturation of Lipid Protein Complexes as a Cause of Damage by Freezing , Proc Roy Soc (Biol) 147:427, 1957;.
16 +
Mark, V. H.; Chato, J. C.; Eastman, F. G.; Aronow, S.; and Ervin, F. R.:  Localized Cooling in the Brain , Science 134:1520, 1961;.
17 +
Marshall, C.; Nims, L. F.; and Stone, W. E.:  Chemical Changes in Cerebral Cortex Following Local Thermocoagulation and Freezing , Yale J Biol Med 13:485, 1941;.
18 +
Meryman, H. T.:  Mechanics of Freezing in Living Cells and Tissue , Science 124:515, 1956;.
19 +
Rowbotham, G. F.; Haigh, A. L.; and Leslie, W. G.:  Cooling Cannula for Use in the Treatment of Cerebral Neoplasms , Lancet 1:12, 1959;.
20 +
Siegfried, J.; Ervin, F. R.; Miyazaki, Y.; and Mark, V. H.:  Localized Cooling of the Central Nervous System: I. Neurophysiological Studies in Experimental Animals , J Neurosurg 19:840, 1962;.
21 +
Tytus, J. S., and Ries, L.:  Further Observation on Rapid Freezing and Its Possible Application to Neurosurgical Techniques , Bull Mason Clin 15:51, 1961;.
22 +
Walton, G.:  Cold Shock of Spermatozoa , Proc Roy Soc (Biol) 147:508, 1957;.

First Page Preview

First page PDF preview

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

1 +
Balthasar, K.:  Gezielte Kalteshaden in der Grosshimmide der Katze , Deutsch Z Nervenheilk 176:173, 1957;.
2 +
Bielschowsky, M., and Valentin, B.:  Die histologischen Veränderungen in durchfrorenen Nervenstrecken , J Psychol Neurol (Leipzig) 29:133, 1922;.
3 +
Cooper, I. S.: Personal communication to the authors.
4 +
Cooper, I. S.:  A Cryogenic Method for Physiologic Inhibition and Production of Lesions in the Brain , J Neurosurg 19:853, 1962;.
5 +
Denny-Brown, D.; Adams, R. D.; Brenner, C.; and Doherty, M. M.:  The Pathology of Injury to Nerve Induced by Cold , J Neuropath Exp Neurol 4:305, 1945;.
6 +
Dondey, M.; Albe-Fessard, D.; and LeBeau, J.:  Refroidissement temporaire et localisé de structures cérébrales profondes: Resultats physiologiques preliminaires , Rev Neurol (Paris) 105:186, 1961;.
7 +
Fox, R. H.:  Local Cooling in Man , Brit Med Bull 17:14, 1961;.
8 +
Fuhrman, F. A., and Crismon, J. M.:  Studies on Gangrene Following Cold Injury: I. A Method for Producing Gangrene by Means of Controlled Injury by Cold , J Clin Invest 26:229, 1947;.
9 +
Hammel, H. T.:  Thermoregulatory Responses to Hypothalamic Cooling in Unanesthetized Dogs , Amer J Physiol 198:481, 1960;.
10 +
Hass, G. H., and Taylor, C. B.:  Quantitative Hypothermal Method for Production of Local Injury of Tissue , Arch Path 45:563, 1948;.
11 +
Klatzo, I.; Piraux, A.; and Laskowski, E. J.:  The Relationship Between Edema, Blood-Brain Barrier, and Tissue Element in a Local Brain Injury , J Neuropath Exp Neurol 17:548, 1958;.
12 +
Kreyberg, L., and Retness, P.:  La stase experimentale méthode pour la mettre en évidence au moyende préparations spéciales , CR Soc Biol (Paris) 106:895, 1931;.
13 +
Kulka, J. P., and Brigham, R. B.:  Circulatory Change in Cold Injury of the Mouse Ear: An Experimental Approach to the Pathogenesis of Vasospastic Tissue Damage , Amer J Path 35:705, 1959;.
14 +
Lewis, R. B.: Cold Injury , Bristol, Conn: Hildreth Press, Inc., 1952;, p 24.
15 +
Lovelock, J. E.:  The Denaturation of Lipid Protein Complexes as a Cause of Damage by Freezing , Proc Roy Soc (Biol) 147:427, 1957;.
16 +
Mark, V. H.; Chato, J. C.; Eastman, F. G.; Aronow, S.; and Ervin, F. R.:  Localized Cooling in the Brain , Science 134:1520, 1961;.
17 +
Marshall, C.; Nims, L. F.; and Stone, W. E.:  Chemical Changes in Cerebral Cortex Following Local Thermocoagulation and Freezing , Yale J Biol Med 13:485, 1941;.
18 +
Meryman, H. T.:  Mechanics of Freezing in Living Cells and Tissue , Science 124:515, 1956;.
19 +
Rowbotham, G. F.; Haigh, A. L.; and Leslie, W. G.:  Cooling Cannula for Use in the Treatment of Cerebral Neoplasms , Lancet 1:12, 1959;.
20 +
Siegfried, J.; Ervin, F. R.; Miyazaki, Y.; and Mark, V. H.:  Localized Cooling of the Central Nervous System: I. Neurophysiological Studies in Experimental Animals , J Neurosurg 19:840, 1962;.
21 +
Tytus, J. S., and Ries, L.:  Further Observation on Rapid Freezing and Its Possible Application to Neurosurgical Techniques , Bull Mason Clin 15:51, 1961;.
22 +
Walton, G.:  Cold Shock of Spermatozoa , Proc Roy Soc (Biol) 147:508, 1957;.

Correspondence

Submit a Letter
CME Course for:


You need to register in order to view this quiz.


To understand the clinical management of acute heart failure syndromes.
Accreditation Information The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
To view and print your certificate and access a summary of your CME courses go to My CME.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s “Cited By” API will populate this tab (http://www.crossref.org/citedby.html).
Compression-Only CPR: Pushing the Science Forward
Cone
AAM 2010;304:1493-1495.
All you need to read in the other general journals
BMJ 2010;341:c5893-c1494.
Submit a Comment

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

© 2012 American Medical Association. All Rights Reserved.
Powered bySilverchair Information Systems