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Korn-Lubetzki et al have described the case of a young woman who presented with OMS preceded by psychiatric symptoms diagnosed as severe anxiety. Findings of oncologic evaluation were negative, the cerebrospinal fluid protein level was elevated, and antistreptolysin O titer was high; however, the authors have not mentioned whether anti-NMDAR or any other antibodies related to OMS have been identified in the serum/cerebrospinal fluid of their patient. The clinical course is also different from that of our patient, who presented with symptoms of depression and psychomotor slowing, gait instability, and OMS followed by the typical phases of anti–NMDA receptor encephalitis (akinetic, hyperkinetic, and then slow recovery). Their patient also had a dramatic improvement with intravenous immunoglobulin therapy. Despite differences in the possible etiology, the case described by the authors illustrates well the importance of recognizing OMS in possible paraneoplastic, postinfectious, or autoimmune etiologies. In most cases, this justifies early treatment with intravenous immunoglobulin.1
Correspondence: Dr Lalive, Department of Clinical Neurosciences, Division of Neurology, University Hospital of Geneva, Rue Gabrielle Perret-Gentil 4, 1211 Geneva, Switzerland (patrice.lalive@hcuge.ch).
Financial Disclosure: None reported.
Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal
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