0
Correspondence |

Association Between Pathologic Gambling and Parkinsonian Therapy as Detected in the Food and Drug Administration Adverse Event Database—Reply

M. Leann Dodd, MD
[+] Author Affiliations

Copyright 2006 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

More Author Information
Arch Neurol. 2006;63(2):300-300. doi:10.1001/archneur.63.2.300-a
Text Size: A A A
Published online

In reply

I very much appreciate the data presented by Szarfman and colleagues, which were prepared using the Food and Drug Administration AERS database and the MGPS statistical algorithm. These new data provide further support to the conclusions presented in our article,1 and I thank them for presenting their findings. The prominent occurrence of pramipexole seen in their data adds support to the position that a relationship between that particular dopamine agonist and impulsive behaviors is strong. I further contend that disproportionate dopamine D3 agonism (especially seen with pramipexole) as a substrate for pathologic gambling seems too obvious to ignore.

AUTHOR INFORMATION

Correspondence: Dr Dodd, Department of Psychiatry and Psychology, Mayo Clinic, 200 First St SW, Rochester, MN 55905 (dodd.maryellen@mayo.edu).

REFERENCES

Dodd  ML, Klos  KJ, Bower  JH, Geda  YE, Josephs  KA, Ahlskog  JE. Pathological gambling caused by drugs used to treat Parkinson disease. Arch Neurol 2005;621377- 1381
PubMed

First Page Preview

First page PDF preview

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Dodd  ML, Klos  KJ, Bower  JH, Geda  YE, Josephs  KA, Ahlskog  JE. Pathological gambling caused by drugs used to treat Parkinson disease. Arch Neurol 2005;621377- 1381
PubMed

Correspondence

CME Course for:


You need to register in order to view this quiz.


To understand the clinical management of acute heart failure syndromes.
Accreditation Information The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
To view and print your certificate and access a summary of your CME courses go to My CME.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s “Cited By” API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...
Articles Related By Topic
Related Topics
PubMed Articles