In reply Trinka et al remark correctly in their interesting letter that epilepsy is found in some patients with juvenile-onset HD.In our study, epilepsy was excluded in the standard symptom list, because it is a rare symptom in patients with adultonset HD, and our sample only contained 4 patients with disease onset when they were younger than 21 years of age. The medical records and the neuropsychiatrist treating these 4juvenileonset cases report no seizures for any of the patients. These 4 patients include the 2 patients with (CAG) trinucleotide repeat numbers higher than 60 mentioned by Trinka et al. Therefore, we believe that neither our data nor the data of Trinka et al lead to the conclusion that a correlation exists between the presence of epilepsy and the size of the (CAG) trinucleotide expansion. We agree that molecular investigation of a large series of patients with HD will be
Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal
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