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Delayed Varicella Vasculopathy

Grant T. Liu, MD
Arch Neurol. 1991;48(9):900-900. doi:10.1001/archneur.1991.00530210026013
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To the Editor.  —I read with great interest the article by Caekebeke et al.1 They carefully document a case of a 5-year-old boy who suffered from an acute hemiparesis 3 and 9 months after a chickenpox infection.However, I disagree with their contention that this association had not been previously reported. Earlier, Holmes and I2 described a 3½-year-old boy who developed a hemiparesis 1 month after a varicella infection. Eda et al3 in 1983 had already reported four similar cases, and then Kamholz and Tremblay4 documented another.The ages of the six patients2-4 ranged from 1 to 6 years of age, and the time between onset of varicella and onset of hemiparesis varied from 1 to 3 months. Cranial imaging studies revealed infarcts involving the basal ganglia and internal capsule in all six cases. Caekebeke and coworkers' patient1 differs slightly because he had two

REFERENCES

Caekebeke JFV, Boudewyn Peters AC, Vandvik B, Brouwer OF, de Bakker HM.  Cerebral vasculopathy associated with primary varicella infection . Arch Neurol . 1990;;47:1033-1035.
Liu GT, Holmes GL.  Varicella with delayed contralateral hemiparesis detected by MRI . Pediatr Neurol . 1990;;6:131-134.
Eda I, Takashima S, Takeshita K.  Acute hemiplegia with lacunar infarct after varicella infection in childhood . Brain Dev . 1983;;5:494-499.
Kamholz J, Tremblay G.  Chickenpox with delayed contralateral hemiparesis caused by cerebral angiitis . Ann Neurol . 1985;;18:358-360.
Walker RJ, Gammal TE, Allen MB.  Cranial arteritis associated with herpes zoster: case report with angiographic findings . Radiology . 1973;;107:109-110.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Caekebeke JFV, Boudewyn Peters AC, Vandvik B, Brouwer OF, de Bakker HM.  Cerebral vasculopathy associated with primary varicella infection . Arch Neurol . 1990;;47:1033-1035.
Liu GT, Holmes GL.  Varicella with delayed contralateral hemiparesis detected by MRI . Pediatr Neurol . 1990;;6:131-134.
Eda I, Takashima S, Takeshita K.  Acute hemiplegia with lacunar infarct after varicella infection in childhood . Brain Dev . 1983;;5:494-499.
Kamholz J, Tremblay G.  Chickenpox with delayed contralateral hemiparesis caused by cerebral angiitis . Ann Neurol . 1985;;18:358-360.
Walker RJ, Gammal TE, Allen MB.  Cranial arteritis associated with herpes zoster: case report with angiographic findings . Radiology . 1973;;107:109-110.

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