To the Editor. —We read with interest the article by Elizan et al in the January issue of the Archives.1 The authors suggest that the early combination of selegiline and levodopa initiated at the "earliest clinical expression of the disease process" seems a most reasonable approach. They base this suggestion on their observation that patients receiving selegiline alone experience a dramatic improvement in parkinsonian score following the addition of levodopa (Sinemet). As selegiline alone provides little or no symptomatic benefit as monotherapy in early Parkinson's disease,2 it is not surprising that a significant symptomatic response was observed with the addition of levodopa. As the authors point out, it is not known how the response to levodopa and selegiline compares with that which could be achieved with levodopa alone, a dopamine agonist alone, or the combination of selegiline and a dopamine agonist.The rationale for the use of selegiline in
Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal
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