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Cognitive Deficits and Emotional Dysfunction in Multiple Sclerosis

Robert M. Herndon, MD
Arch Neurol. 1990;47(1):18-18. doi:10.1001/archneur.1990.00530010026013
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This issue of the Archives contains two reviews prepared on behalf of the Cognitive Function Study Group of the National Multiple Sclerosis Society. These articles are a response to the need for more and better information on the mental and emotional effects of multiple sclerosis, but they also serve as an example of an approach that could be useful in other neurologic disorders.

See also pp 94 and 98.

The varied conclusions and varied methodology used by investigators to study cognitive dysfunction and affective disorders in patients with multiple sclerosis and other neurologic disorders, while providing useful information, have made it difficult or impossible to compare studies. In addition, since most of the studies are based on highly selected samples, the results are applicable only in very restricted, often poorly defined, subsets of patients. Both articles review important clinical research areas and include recommendations regarding research standards that, if implemented,

REFERENCES

Peyser JM, Rao SM, LaRocca NG, Kaplan E.  Guidelines for neuropsychological research in multiple sclerosis . Arch Neurol . 1990;;47:94-97.
Minden SL, Schiffer RB.  Affective disorders in multiple sclerosis: review and recommendations for clinical research . Arch Neurol . 1990;;47:98-104.

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Peyser JM, Rao SM, LaRocca NG, Kaplan E.  Guidelines for neuropsychological research in multiple sclerosis . Arch Neurol . 1990;;47:94-97.
Minden SL, Schiffer RB.  Affective disorders in multiple sclerosis: review and recommendations for clinical research . Arch Neurol . 1990;;47:98-104.

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