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Magnetic Resonance Imaging in Moyamoya Disease

Loren A. Rolak, MD
Arch Neurol. 1989;46(1):14-14. doi:10.1001/archneur.1989.00520370016009
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To the Editor.  —I wish to congratulate Bruno and colleagues1 on their excellent study of magnetic resonance imaging (MRI) in young adults with cerebral infarction due to moyamoya disease. I would like to add to their discussion by interjecting a note of caution about the nonspecificity of MRI in this condition.We reported the first use of MRI in moyamoya disease2 in a patient initially thought to have multiple sclerosis (MS). Our patient, like most of those in the article by Bruno et al, was a young woman with fluctuating neurologic findings in whom the MRI showed multifocal bilateral areas of increased signal intensity ranging in size from 2 mm to 3 cm, with an appearance identical to that of MS plaques. Unlike their patients, her lesions were not concentrated in watershed areas, nor was the middle cerebral artery signal-void flow sign absent. Our patient also had abnormal brain-stem

REFERENCES

Bruno A, Yuh WTC, Biller J, et al:  Magnetic resonance imaging in young adults with cerebral infarction due to moyamoya . Arch Neurol 1988;;45:303-306.
Rolak LA, Rokey R:  Magnetic resonance imaging in moyamoya disease . J Child Neurol 1986;;1:67-70.
Iivanainen M, Vuolio M, Halonen V:  Occlusive disease of intracranial main arteries with collateral networks (moyamoya disease) in adults . Acta Neurol Scand 1973;;49:307-322.
Drayer BP, Burger P, Hurwitz B, et al:  Magnetic resonance imaging in multiple sclerosis: Decreased signal in thalamus and putamen . Ann Neurol 1987;;22:546-550.

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Bruno A, Yuh WTC, Biller J, et al:  Magnetic resonance imaging in young adults with cerebral infarction due to moyamoya . Arch Neurol 1988;;45:303-306.
Rolak LA, Rokey R:  Magnetic resonance imaging in moyamoya disease . J Child Neurol 1986;;1:67-70.
Iivanainen M, Vuolio M, Halonen V:  Occlusive disease of intracranial main arteries with collateral networks (moyamoya disease) in adults . Acta Neurol Scand 1973;;49:307-322.
Drayer BP, Burger P, Hurwitz B, et al:  Magnetic resonance imaging in multiple sclerosis: Decreased signal in thalamus and putamen . Ann Neurol 1987;;22:546-550.

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