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Bilateral Papilledema and Self-Mutilation

Curtis Margo, MD; Kenneth Adams, MD
Arch Neurol. 1982;39(9):604-604. doi:10.1001/archneur.1982.00510210074032
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To the Editor.—  Persons with self-inflicted ocular mutilation have an unusual form of psychotic behavior1 that, on occasion, may be associated with abnormal purine metabolism.2,3 We recently helped care for a 29-year-old woman who sustained self-inflicted facial trauma and in whom bilateral papilledema later developed. Her clinical course suggested the presence of an intracranial mass, but the results of her neurologic evaluation were unremarkable. Pathologic examination of her self-enucleated right eye showed that the papilledema was related to meningitis of the optic nerve from apparently self-introduced intraorbital foreign material.

Report of a Case.—  A 29-year-old woman had a one-year history of compulsive self-mutilation, characterized mainly by bouts of punching herself in the face. Her behavior was not modified by major tranquilizers. She had been hospitalized twice for self-inflicted trauma, including a superficial laceration of her throat. During her last hospitalization, she sustained bilateral corneal abrasions, conjunctival lacerations, and

REFERENCES

Yank HK, Brown GC, Magargal LE:  Self-inflicted ocular mutilation . Am J Ophthalmol 1981;;91:658-663.
Van Woert MH, Yip LC, Balis ME:  Purine phosphoribosyltransferase in Giles de la Tourette syndrome . N Engl J Med 1977;;296:210-212.
Nyhan WL:  Clinical features of the Lesch-Nyhan syndrome . Arch Intern Med 1972;;130:186-192.
Hedges TR:  Papilledema: Its recognition and relation to increased intracranial pressure . Surv Ophthalmol 1975;;19:201-223.
Hart WM, Burke RM, Klingele TG, et al:  Bilateral optic sheath meningiomas . Arch Ophthalmol 1980;;98:149-151.
Trobe JD, Glaser JS, Laflamme P:  Thyroid optic neuropathy, clinical profile and rationale for management . Arch Ophthalmol 1978;;96:1199-1209.
Bowen DI:  Self-inflicted orbitocranial injury with a ballpoint pen . Br J Ophthalmol 1971;;55:427-430.
Bank CW:  Orbital foreign body simulating a malignant melanoma . Br J Ophthalmol 1967;;51:566-567.
Heyner FJ, Passmore JW:  Pseudotumor of the orbit caused by retained foreign body . Am J Ophthalmol 1965;;59:490-492.

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Yank HK, Brown GC, Magargal LE:  Self-inflicted ocular mutilation . Am J Ophthalmol 1981;;91:658-663.
Van Woert MH, Yip LC, Balis ME:  Purine phosphoribosyltransferase in Giles de la Tourette syndrome . N Engl J Med 1977;;296:210-212.
Nyhan WL:  Clinical features of the Lesch-Nyhan syndrome . Arch Intern Med 1972;;130:186-192.
Hedges TR:  Papilledema: Its recognition and relation to increased intracranial pressure . Surv Ophthalmol 1975;;19:201-223.
Hart WM, Burke RM, Klingele TG, et al:  Bilateral optic sheath meningiomas . Arch Ophthalmol 1980;;98:149-151.
Trobe JD, Glaser JS, Laflamme P:  Thyroid optic neuropathy, clinical profile and rationale for management . Arch Ophthalmol 1978;;96:1199-1209.
Bowen DI:  Self-inflicted orbitocranial injury with a ballpoint pen . Br J Ophthalmol 1971;;55:427-430.
Bank CW:  Orbital foreign body simulating a malignant melanoma . Br J Ophthalmol 1967;;51:566-567.
Heyner FJ, Passmore JW:  Pseudotumor of the orbit caused by retained foreign body . Am J Ophthalmol 1965;;59:490-492.

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