0
Article |

Serum Dopamine-β-Hydroxylase Activity in Migraine

Fumio Gotoh, MD; Tadashi Kanda, MD; Fumihiko Sakai, MD; Masahiro Yamamoto, MD; Tsuneyuki Takeoka, MD
[+] Author Affiliations

Accepted for publication March 18, 1976.

Reprint requests to Department of Neurology, Keio University Hospital, 35 Shinanomachi Shinjuku-ku, Tokyo, Japan (Dr Gotoh).


Arch Neurol. 1976;33(9):656-657. doi:10.1001/archneur.1976.00500090062012
Text Size: A A A
Published online

• Serum dopamine-β-hydroxylase (DBH) activity was measured during headache-free intervals in 17 patients with migraine and during the headache interval in 16 patients with muscle contraction headache, as well as in 40 normal subjects. The DBH activity was significantly higher in the migraine patients (46.5 ± 4.5 units) than in the controls (24.9 ± 2.4 units), whereas no significant difference was observed between the patients with muscle contraction headache (29.4 ± 4.5 units) and the controls.

REFERENCES

Anthony M, Lance JW:  Current concepts in the pathogenesis and interval treatment of migraine . Drugs 3:153-158, 1972;.
Nielsen KC, Owman C:  Adrenergic innervation of pial arteries related to the circle of Willis in the cat . Brain Res 6:773-776, 1967;.
Gotoh F, Ebihara S, Toyoda M, et al:  Role of autonomic nervous system in autoregulation of human cerebral circulation . Eur Neurol 6:203-207, 1971;/72.
Weinshilboum RM, Thoa NB, Johnson DG, et al:  Proportional release of norepinephrine and dopamine-β-hydroxylase from sympathetic nerves . Science 174:1349-1351, 1971;.
Roffman M, Freedman LS, Battista AF, et al:  Dopamine-β-hydroxylase activity in the vasculature . Fed Proc 32:707, 1973;.
Weinshilboum RM, Raymond FA, Elveback LR, et al:  Serum dopamine-β-hydroxylase activity: Sibling-sibling correlation . Science 181:943-945, 1973;.
Wooten GF, Cardon PV:  Plasma dopamineβ-hydroxylase activity: Elevation in man during cold pressor test and exercise . Arch Neurol 28:103-106, 1973;.
Friedman AP, Finley KH, Graham JR, et al:  Classification of headache: The Ad Hoc Committee on classification of headache . Arch Neurol 6:173-176, 1962;.
Nagatsu T, Udenfriend S:  Photometric assay of dopamine-β-hydroxylase activity in human blood . Clin Chem 18:980-983, 1972;.
Dalessio DJ:  Vascular permeability and vasoactive substances: Their relationship to migraine , in Bronica JJ (ed): Advances in Neurology . New York, Raven Press, 1974;, vol 4, pp 395-401.

First Page Preview

First page PDF preview

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Anthony M, Lance JW:  Current concepts in the pathogenesis and interval treatment of migraine . Drugs 3:153-158, 1972;.
Nielsen KC, Owman C:  Adrenergic innervation of pial arteries related to the circle of Willis in the cat . Brain Res 6:773-776, 1967;.
Gotoh F, Ebihara S, Toyoda M, et al:  Role of autonomic nervous system in autoregulation of human cerebral circulation . Eur Neurol 6:203-207, 1971;/72.
Weinshilboum RM, Thoa NB, Johnson DG, et al:  Proportional release of norepinephrine and dopamine-β-hydroxylase from sympathetic nerves . Science 174:1349-1351, 1971;.
Roffman M, Freedman LS, Battista AF, et al:  Dopamine-β-hydroxylase activity in the vasculature . Fed Proc 32:707, 1973;.
Weinshilboum RM, Raymond FA, Elveback LR, et al:  Serum dopamine-β-hydroxylase activity: Sibling-sibling correlation . Science 181:943-945, 1973;.
Wooten GF, Cardon PV:  Plasma dopamineβ-hydroxylase activity: Elevation in man during cold pressor test and exercise . Arch Neurol 28:103-106, 1973;.
Friedman AP, Finley KH, Graham JR, et al:  Classification of headache: The Ad Hoc Committee on classification of headache . Arch Neurol 6:173-176, 1962;.
Nagatsu T, Udenfriend S:  Photometric assay of dopamine-β-hydroxylase activity in human blood . Clin Chem 18:980-983, 1972;.
Dalessio DJ:  Vascular permeability and vasoactive substances: Their relationship to migraine , in Bronica JJ (ed): Advances in Neurology . New York, Raven Press, 1974;, vol 4, pp 395-401.

Correspondence

CME Course for:


You need to register in order to view this quiz.


To understand the clinical management of acute heart failure syndromes.
Accreditation Information The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
To view and print your certificate and access a summary of your CME courses go to My CME.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s “Cited By” API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.