Author Contributions:Study concept and design: Cruchaga and Goate. Acquisition of data: Graff, Chiang, Wang, Spiegel, Mayo, Norton, and Morris. Analysis and interpretation of data: Cruchaga, Hinrichs, Spiegel, Bertelsen, and Goate. Drafting of the manuscript: Cruchaga, Graff, Chiang, and Goate. Critical revision of the manuscript for important intellectual content: Graff, Wang, Hinrichs, Spiegel, Bertelsen, Mayo, Norton, Morris, and Goate. Statistical analysis: Cruchaga, Hinrichs, and Bertelsen. Obtained funding: Morris and Goate. Administrative, technical, and material support: Graff, Chiang, Spiegel, Mayo, Norton, and Morris. Study supervision: Graff and Goate.