0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Images in Neurology |

Magnetic Resonance Imaging Findings in a Patient With Isolated Histoplasma Brain Abscess

Anit Parihar, MD; Vaishali Tomar, MBBS; Bal K. Ojha, MCh; Nuzhat Husain, MD; Rakesh K. Gupta, MD
Arch Neurol. 2011;68(4):534-535. doi:10.1001/archneurol.2011.59.
Text Size: A A A
Published online

Extract

A 34-year-old woman presented with progressive headache of 3 months' duration but was otherwise in good health with no abnormal neurological signs. The chest radiograph was unremarkable. Brain magnetic resonance imaging showed a well-defined ring-enhancing lesion in the left occipital region with perifocal edema. The capsule was hypointense with intracavitary projections seen arising from the wall on T2-weighted axial images. These projections were hyperintense on diffusion-weighted images with an apparent diffusion coefficient value of 0.51 × 10−3 mm2/s (Figure 1). A preoperative diagnosis of fungal abscess was subsequently confirmed after surgery and on histologic findings. A Gomori methenamine silver stain revealed round bodies of Histoplasma capsulatum in foamy histiocytes (Figure 2). She was treated with antifungal drugs and was without any symptoms at 6 months' follow-up.

Figures in this Article

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview

Figures

Place holder to copy figure label and caption
Figure 1.

Brain magnetic resonance image shows a well-encapsulated cystic lesion with hypointense intracavitary projections (A) with ring enhancement seen on the postcontrast-enhancing medium study (B). Note the increased signal of the projections consistent with restricted diffusion (C).

Graphic Jump Location
Place holder to copy figure label and caption
Figure 2.

Views of foamy histiocytes. A, Photomicrograph shows foamy histiocytes (hematoxylin-eosin, original digital magnification ×525). B, Photomicrograph shows silver-stained intracytoplasmic round bodies of Histoplasma capsulatum (arrows) in foamy histiocytes (Gomori methenamine silver, original digital magnification ×525).

Graphic Jump Location

Tables

References

Correspondence

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

182 Views
0 Citations
×

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Collections
PubMed Articles
Jobs
JAMAevidence.com

The Rational Clinical Examination: Evidence-Based Clinical Diagnosis
Original Article: Does This Patient Have a Torn Meniscus or Ligament of the Knee?

The Rational Clinical Examination: Evidence-Based Clinical Diagnosis

brightcove.createExperiences();