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Images in Neurology |

Focal Hyperhidrosis in Tumefactive Multiple Sclerosis

Raffaele Iorio, MD; Domenico Plantone, MD; Giovanni Frisullo, MD, PhD; Viviana Nociti, MD; Agata Katia Patanella, MD; Pietro Attilio Tonali, MD; Cesare Colosimo, MD; Anna Paola Batocchi, MD, PhD
Arch Neurol. 2010;67(11):1407-1408. doi:10.1001/archneurol.2010.274.
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Sweating abnormalities associated with diseases of the central nervous system can occur in syringomyelia,1 lateral medullary infarction,2 or hemispheric2 or hypothalamic strokes.3 Hyperhidrosis has been reported in some adults2 and in a child3 affected by multiple sclerosis (MS). This condition, as a symptom of MS, is considered uncommon.2

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Figure 1.

Focal hyperhidrosis of the left hand. The image was captured when the patient experienced emotional distress during the neurologic examination.

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Figure 2.

Brain magnetic resonance imaging in a patient with multiple sclerosis. A-C, Multiplanar high-resolution T2-weighted fluid-attenuated inversion recovery images. The heterogeneous huge tumorlike lesion extends along the right temporal stem and involves the hippocampus and the limbic circuit, with significant edema of the mass effect type. D, Axial postcontrast T1-weighted images. After contrast injection, the peripheral enhancing rim is typically discontinuous. Other white matter lesions are present in the contralateral hemisphere.

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