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Images in Neurology |

Scattered Cerebral Microbleeds Due to Cardiac Myxoma

Peter Vanacker, MD; Natalie Nelissen, MD; Koen Van Laere, MD, PhD; Vincent N. Thijs, MD
Arch Neurol. 2009;66(6):796-797. doi:10.1001/archneurol.2009.63.
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Multiple scattered microbleeds on gradient-echo magnetic resonance imaging may be found as a consequence of cerebral microangiopathy due to hypertension, amyloid angiopathy, or hemorrhagic conversion of cardiac emboli or artery to artery embolization.1 Amyloid deposition in the setting of Alzheimer disease or intracerebral hemorrhage can be studied in humans by performing carbon 11 ([11C])–labeled Pittsburgh Compound B positron emission tomography. This positron emission tomography tracer has a high affinity for vascular as well as plaque β-amyloid and is increasingly being used in the evaluation of cognitive disturbance and stroke.2

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Magnetic resonance images, distribution volume ratio image of positron emission tomography, and an echocardiogram. Gradient-echo magnetic resonance imaging shows numerous microhemorrhages in the fronto-occipital lobes and basal ganglia (A), some of which are diffusion restrictive (B). C, Distribution volume ratio images of carbon 11–labeled Pittsburgh Compound B positron emission tomography exclude an increased β-amyloid burden. D, An echocardiogram reveals a left atrial myxoma. LA indicates left atrium; LV, left ventricle.

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