0
Book Review |

The Legacy of Tracy J. Putnam and H. Houston Merritt: Modern Neurology in the United States

Arch Neurol. 2009;66(3):415. doi:10.1001/archneurol.2009.34.
Text Size: A A A
Published online

Extract

Notable partnerships in medicine and science have included Hubel and Wiesel, Watson and Crick, Jacob and Monod, Jasper and Penfield, and Kety and Schmidt, among others. Their joint efforts were synergistic and mutually beneficial. Their combined careers allowed both to prosper and brought esteem by colleagues that was equally shared. Rowland describes vividly the partnership of Putnam and Merritt in their research in 1938 to develop the anticonvulsant diphenylhydantoin (now phenytoin) with the trade name Dilantin (Pfizer, New York, New York). The scientific achievement of Putnam and Merritt is monumental, as diphenylhydantoin has proved to be a major contribution to combat epilepsy. Their personal outcomes, however, were in stark contrast compared with other scientific partnerships and the reasons and facts for this disparity, as provided by Rowland in graphic style, is a story of Shakespearean proportion. The real story conveyed by Rowland is the personal and professional lives and relationships between the two men. Rowland knows the full story because he was there at Columbia and the Neurological Institute for most of it. He never knew Putnam personally but has meticulously reviewed the archives of the medical school and Presbyterian Hospital to obtain the essential facts and the flavor of the times. He did know Merritt well from 1950 until Merritt died in 1979.

Topics

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
/>
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();