0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Correspondence |

Differential Diagnosis Between Acute Disseminated Encephalomyelitis and Multiple Sclerosis During the First Episode—Reply

Jérôme de Seze, MD, PhD
Arch Neurol. 2008;65(5):672-677. doi:10.1001/archneur.65.5.677-a.
Text Size: A A A
Published online

Extract

In reply

My coauthors and I thank Tavazzi and colleagues for their interesting remarks. We apologize for missing some references, especially the article by Marchioni et al1 from 2005. This very interesting article mostly referred to postinfectious inflammatory disorders rather than ADEM. It focused on postinfectious disorders with central nervous system involvement but also peripheral nervous system involvement, with about 40% of cases having peripheral nervous system lesions and only 20% having cerebral involvement. In this study, 80% of patients had myelitis as compared with 65% in our study.1,2 Furthermore, the study by Marchioni and colleagues was not performed to assess the risk to evolve to clinically definite MS. We think that the designs of the 2 studies were clearly different, probably owing in part to the lack of clear definition of what ADEM is. It is surprising to observe that no patients in the study by Marchioni and colleagues were evaluated for MS as compared with about 30% in our study and others.14

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

26 Views
4 Citations
×

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Collections
PubMed Articles
Jobs
brightcove.createExperiences();