Correspondence |

Benign Tremulous Parkinsonism

David S. Russell, MD, PhD
Arch Neurol. 2006;63(9):1346. doi:10.1001/archneur.63.9.1346-a.
Text Size: A A A
Published online


Drs Josephs, Matsumoto, and Ahlskog provide an excellent characterization of a Parkinson disease subtype that is often discussed anecdotally, but generally with little rigor.1 I generally agree with their analysis and find interesting their finding of a high proportion of affected relatives. Yet, I would like to add 2 notes of caution, based on my admittedly anecdotal experience with such patients.

First, I would like to emphasize that while “benign” in terms of years of slow progression and the relative lack of muscle rigidity, patients with Parkinson disease of this subtype, as the authors note, often have a markedly severe tremor, which they consider exhausting and tormenting—ie, far from “benign.” Patients in this group have often been among my most desperate patients despite their minimal rigidity and bradykinesia.

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours





Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Topics
PubMed Articles

The Rational Clinical Examination
Make the Diagnosis: Parkinsonism

The Rational Clinical Examination
Original Article: Does This Patient Have Parkinson Disease?