Images in Neurology |

Magnetic Resonance Imaging in Poliomyelitis

Anwar Haq, MRCP, MD; Mohammad Wasay, MD, FRCP(UK)
Arch Neurol. 2006;63(5):778. doi:10.1001/archneur.63.5.778.
Text Size: A A A
Published online


Polio is an ancient disease. Involvement of anterior horn cells due to viral infection is the pathological mechanism underlying this condition. It remains to be a clinical diagnosis because most of the time, stool cultures are negative for poliovirus. Recent advances in magnetic resonance imaging may be helpful in establishing a definite diagnosis of poliomyelitis in addition to a clinical picture consistent with polio.

A 28-year-old man was admitted to the hospital with a 4-day history of progressive weakness and low-grade fever. His neurological examination revealed normal mental status and cranial nerves, flaccid weakness of both lower extremities and left upper extremity, absent reflexes, flexor plantar responses, and normal sensory examination results. Cerebrospinal fluid examination findings showed 28 cells, predominantly lymphocytes, and normal glucose and protein levels. The patient had no history of polio vaccination, but his 6-month-old daughter was recently vaccinated with an oral polio vaccine. Results from a nerve conduction examination and electromyography were normal. T2-weighted magnetic resonance imaging showed hyperintensities involving bilateral anterior horn cells (Figure 1 and Figure 2).

Figures in this Article

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
First page PDF preview


Place holder to copy figure label and caption
Figure 1.

T2-weighted magnetic resonance image of cervical spine in sagittal plane showing hyperintense signal involving anterior horn cells extending from C3 through C7 (arrow).

Graphic Jump Location
Place holder to copy figure label and caption
Figure 2.

T2-weighted magnetic resonance image of cervical spine in axial plane showing hyperintense signal involving anterior horn cells (arrow). Inset, the level of this axial section.

Graphic Jump Location




Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Topics
PubMed Articles