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History of Neurology: Seminal Citation |

Uncal Herniation

Boby Varkey Maramattom, MD, DM; Eelco F. M. Wijdicks, MD
Arch Neurol. 2005;62(12):1932-1935. doi:10.1001/archneur.62.12.1932.
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It seems likely that one of the first references to brain herniation were by Collier1 and Alquier,2 who described cerebellar tonsillar herniation. In 1904, Collier reported:

A year later, Alquier described 2 cases that he designated “hetrotope du cervelet dans le canal la rachidien,”2(p1117) which translates to heterotopies of the cerebellum in the spine (rachidian canal). In this article, he wrote about 2 cases with brain tumors and commented that the autopsy showed tissue displacement “forced to migrate due to the pressure effect of the tumor.”2(p1117)

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Figure 1.

A, The title of Kernohan and Woltman’s paper. B, A pathological specimen from the paper, illustrating the groove on the crus cerebri.

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Figure 2.

A, The title page of Reid and Cone’s paper. B, Image shows anesthetized monkey with fixed ipsilateral dilated pupil (top) and corresponding lesion (bottom).

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