Functional MRI was performed using a 3.0-T scanner 3 days after stroke onset. The T1-weighted axial images were included as anatomical images. The blood oxygen level–dependent contrast images consisted of single-shot echo-planar imaging gradient-echo images. Imaging variables included an interscan interval of 3000 milliseconds, an echo time of 40 milliseconds, a matrix of 64 × 64, a field of view of 24 × 24 cm, a flip angle of 90°, and a slice thickness of 6 mm for a total of 20 contiguous slices covering the brain. The motor task for imaging was repetitive thumb-index tapping. The paradigms comprised 3 trials, each consisting of rest–right-hand task–rest–left-hand task, with each rest or task lasting 24 seconds. Visual cues guided the patient through the series of successive tasks and rest periods. There were 3 right-hand task periods, 3 left-hand task periods, and 6 rest periods. The total duration of a run was 384 seconds. Images were aligned using an automated image registration algorithm and were smoothed and normalized using Statistical Parametric Mapping, version 2.0 (University College London, London, England). Statistical analysis was then performed on the pooled data using Statistical Parametric Mapping by setting up a contrast between the rest and the task conditions. The resulting z-maps were thresholded using the criteria of z-score height (P < .001) and cluster size (P < .05). Functional MRI demonstrated that the left sensorimotor cortex was activated during right-hand movement, whereas the bilateral sensorimotor cortex and the right supplementary motor area were activated during left-hand movement (Figure 2).