The treatment approach to patients with MG should be individualized according to patient complaints, degree of weakness, age, and other comorbid conditions. In general, patients with purely ocular myasthenia should start taking cholinesterase inhibitors, with many patients improving. If symptoms persist, immunosuppression might be necessary using corticosteroids, azathioprine, or both. Patients with generalized MG may get some benefit from using cholinesterase inhibitors, but progression of symptoms or crisis may occur if immunosuppression is not instituted. Thymectomy is considered in all patients with generalized MG, the best candidates being young, healthy, and recently diagnosed (<2 years). Generally, patients are also started on prednisone therapy (60-80 mg/d). The addition of azathioprine allows for early corticosteroid weaning. Patients with borderline respiratory function should initiate corticosteroid use in the inpatient setting, with strong consideration for precorticosteroid plasmapheresis or IVIG therapy.