We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

The Office Tensilon Test for Ocular Myasthenia Gravis

Marjorie E. Seybold, MD
Arch Neurol. 1986;43(8):842-843. doi:10.1001/archneur.1986.00520080080028.
Text Size: A A A
Published online


The Tensilon (intravenous edrophonium chloride) test is a frequently used and frequently useful office test for myasthenia gravis (MG). The main controversies concerning the test are the reasons for administering it and the style in which it is administered.

Tensilon testing is useful as a diagnostic test for ocular MG but not as a means of adjusting medical treatment for this condition. Myasthenic extraocular muscles, especially the eyelids, usually respond dramatically in the untreated patient. Similarly, ocular movement, although often not restored completely to normal, is generally improved with the administration of Tensilon. In contrast, Tensilon administration as a means of judging drug dosage is far less useful. The real question with therapy in ocular MG is not whether the eyes will wiggle a little bit more with an intravenous cholinesterase inhibitor but whether a satisfactory (to the patient) response to oral cholinesterase inhibitors can be achieved. This determination


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.