We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Autonomic Deficits in Parkinson's Syndrome

Otto Appenzeller, MD, PhD; Jerry E. Goss, MD
Arch Neurol. 1971;24(1):50-57. doi:10.1001/archneur.1971.00480310078007.
Text Size: A A A
Published online


THE occurrence of autonomic dysfunction in Parkinson's syndrome is widely quoted, but most studies are restricted to clinical impressions. The abnormalities attributed to autonomic disturbances in this disease include sialorrhea, seborrhea, excessive sweating, constipation, sphincter disturbances, dysphagia, postural hypotension, blue mottled skin, and other vasomotor abnormalities, heat intolerance and impotence, to name a few. With the introduction of levodopa for the treatment of Parkinson's syndrome, large numbers of patients have come forth, eager to allow evaluation of their clinical state before, and at intervals after, the start of levodopa therapy. We have tested some autonomic function before and during treatment in 25 patients suffering from Parkinson's syndrome and record the findings in this report.

Patients and Methods  Patients were tested before the start of levodopa therapy and after maximum neurological improvement had been achieved. Fifteen patients were receiving no medication at the time of the baseline tests, all drugs


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.