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Neuropathy Induced by Hemorrhage

Bernard M. Patten, MD
Arch Neurol. 1969;21(4):381-386. doi:10.1001/archneur.1969.00480160053006.
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NEUROPATHY produced by hemorrhage is an infrequently diagnosed and poorly understood condition which has a distinct clinical constellation of signs and symptoms permitting early recognition and treatment before paralysis occurs. It is the purpose of this paper to present three illustrative cases and to discuss the pathogenesis and treatment.

Hemorrhage in or around one or more peripheral nerves may be associated with mild or severe pain of acute or subacute onset in the distribution of the involved nerve, followed by motor weakness, atrophy, sensory loss, and loss of the appropriate reflexes. Complete recovery occurs if the hemorrhage is stopped but may be delayed for many months.

Conditions Associated With Hemorrhage-Induced Neuropathy 

Bleeding Disorders.—  Any congenital, acquired, or iatrogenic hemorrhagic disorder may cause hemorrhage into or around a peripheral nerve. This condition has been reported with plasma thromboplastin component and antihemophilic globulin1-5 deficiency, as well as with heparin,

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