We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Comment & Response |

Physiotherapy and Occupational Therapy and Mild to Moderate Parkinson Disease—Reply

Carl E. Clarke, MD1,2; Marion F. Walker, PhD3; Catherine M. Sackley, PhD4
[+] Author Affiliations
1School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham, England
2Department of Neurology, Sandwell and West Birmingham Hospitals NHS Trust, City Hospital, Birmingham, England
3University of Nottingham, Nottingham, England
4King’s College London, London, England
JAMA Neurol. 2016;73(7):894-895. doi:10.1001/jamaneurol.2016.1283.
Text Size: A A A
Published online


In Reply On behalf of the PD REHAB Collaborative Group, we are pleased that the PD REHAB Trial1 has prompted debate. The issues raised are common to the 3 letters24 and all were covered in the original article.1

Eligibility was based on the uncertainty principle. Investigators were mostly uncertain of the value of physiotherapy and occupational therapy in patients with mild to moderate Parkinson disease (PD). So, the results of the trial can only be applied to patients with mild to moderate disease. This is not in conflict with our Cochrane review of physical therapies in PD, which showed short-term benefits in motor function and activities of daily living but, importantly, not in quality of life in more severe disease.5


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





July 1, 2016
Terry Ellis, PhD, PT, NCS; Linda Tickle-Degnen, PhD, OTR/L; Marie Saint-Hilaire, MD, FRCPC
1Center for Neurorehabilitation, Department of Physical Therapy, Boston University, Boston, Massachusetts
2Collaborative Learning & Innovation Complex, Department of Occupational Therapy, Tufts University, Medford, Massachusetts
3Department of Neurology, Boston University School of Medicine, Boston, Massachusetts4Parkinson Disease and Movement Disorders Program, Boston Medical Center, Boston, Massachusetts
JAMA Neurol. 2016;73(7):892-893. doi:10.1001/jamaneurol.2016.1274.
July 1, 2016
Nienke M. de Vries, PhD; Ingrid H. Sturkenboom, PhD; Bastiaan R. Bloem, MD, PhD
1Department of Neurology, Donders Centre for Neuroscience, Radboud University Medical Center, Nijmegen, the Netherlands
2Department of Rehabilitation, Donders Centre for Neuroscience, Radboud University Medical Center, Nijmegen, the Netherlands
JAMA Neurol. 2016;73(7):893-894. doi:10.1001/jamaneurol.2016.1277.
July 1, 2016
Régis Gemerasca Mestriner, PT, PhD
1Pontifical Catholic University of Rio Grande do Sul, Nursing, Nutrition, and Physiotherapy College, Porto Alegre, Rio Grande do Sul, Brazil
JAMA Neurol. 2016;73(7):894. doi:10.1001/jamaneurol.2016.1280.
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...