We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Editorial |

Uncovering Neuroanatomical Networks Responsible for Abnormal Eating Behavior in Frontotemporal Dementia

Jennifer L. Whitwell, PhD1
[+] Author Affiliations
1Department of Radiology, Mayo Clinic, Rochester, Minnesota
JAMA Neurol. 2016;73(3):267-268. doi:10.1001/jamaneurol.2015.4496.
Text Size: A A A
Published online


Magnetic resonance imaging (MRI) is a powerful tool that allows us to not only assess atrophic patterns associated with disease but to start to unravel the complex associations between regional tissue loss and specific clinical symptoms. Patterns of atrophy associated with frontotemporal dementia (FTD) and its clinical variants have been well described and studies have begun to demonstrate that different behavioral symptoms observed across the FTD spectrum have different anatomical loci.16 Changes in one’s eating behavior is a behavioral feature that is particularly hard to measure and, hence, to study accurately with neuroimaging. This could involve the tendency to overeat or cram food in the mouth, indiscriminate eating, oral exploration of inanimate objects, increased selectivity in food choices, or a preference for sweet foods.7 These behaviors are typically best captured with caregiver questionnaires since a loss of insight results in an underestimation of the presence and severity of the behaviors by the patient. These questionnaires are not perfect, however, and are limited by problems with overestimation or underestimation. In addition, the reduced quantitative scale often inherent to these questionnaires (eg, 4-point scale of normal, mild, moderate, severe) can also make neuroimaging analyses difficult.

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...
Articles Related By Topic
Related Collections