Dr Rubino’s parents emphasized the significance of education to him, his 3 sisters, and his brother.1 His father had originally emigrated from Italy. Dr Rubino obtained his undergraduate degree from Bradley University in Peoria, Illinois, where he graduated magna cum laude in 1955 with a bachelor of science degree in mathematics and chemistry. He was then drafted into the US Army and sent to Fort Sam Houston in Houston, Texas. His interest in medicine was cultivated by the pathologist COL Ivey. Dr Rubino later attended medical school at the University of Illinois in 1962 with Alpha Omega Alpha Honor Medical Society distinction. One interesting fact is that Dr Rubino actually completed 2 residencies, the first in psychiatry (Illinois State Psychiatric Institute) and later another in neurology (Northwestern University), and he was board certified in both specialties. His passion was the brain and neurology, and he practiced neurology exclusively throughout his career. However, those who knew Dr Rubino were always amazed by his deep wisdom about patient care in general, his unwavering compassion for and dedication to his patients. He would return to the Edward Hines Jr VA Hospital in Hines, Illinois, where he served as the chief neurologist from 1969 to 1971. His passion was teaching, particularly teaching residents. In 1985 he joined the US Army Reserve, where he rose to lieutenant colonel. Dr Rubino joined the faculty in the Department of Neurology at Loyola University Stritch School of Medicine in 1970 and rose to professor of neurology and acting chairman in 1982. He later served as the director of the Hines/Loyola Neurology Residency Training Program from 1978 to 1989. Dr Rubino trained several personnel at the Veterans Affairs hospital who would later work at Mayo Clinic in Rochester, Minnesota. Later, it was Mayo Clinic in Jacksonville, Florida, that recruited Dr Rubino. As proof of his passion for lifelong teaching, Dr Rubino started a neurology residency at Mayo Clinic in Florida as the co–program director in 2000 along with David J. Capobianco, MD.