This long-term case report describes a woman with idiopathic inflammatory myopathy treated with high-dose immunoablative cyclophosphamide.
To our knowledge, this is the first report of the use of high-dose immunoablative cyclophosphamide (HiCy) therapy in the absence of stem cell rescue in patients with idiopathic inflammatory myopathy.
Article InformationCorresponding Author: Lisa Christopher-Stine, MD, MPH, Division of Rheumatology, Johns Hopkins University School of Medicine, 5200 Eastern Ave, MFL Center Tower, Ste 4500, Baltimore, MD 21224 (firstname.lastname@example.org).
Conflict of Interest Disclosures: Dr Christopher-Stine reports serving on the advisory board; receiving honoraria from Novartis, Mallinckrodt, Walgreens, and Medimmune; and having membership in the advisory board of Idera. She has intellectual property rights in connection with Inova Diagnostics. No other disclosures were reported.
Funding/Support: This study was supported by the Huayi and Siuling Zhang Discovery Fund.
Role of the Funder/Sponsor: The funder had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.