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Comment & Response |

Targeted Temperature Management for Cardiac Arrest

Nathan S. Deal, MD1; Robert B. Schock, PhD2; W. Frank Peacock, MD1
[+] Author Affiliations
1Section of Emergency Medicine, Baylor College of Medicine, Houston, Texas
2Research and Development, Life Recovery Systems, Kinnelon, New Jersey
JAMA Neurol. 2015;72(9):1076. doi:10.1001/jamaneurol.2015.1372.
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To the Editor We read with interest the article by Cronberg et al1 in which cognitive function was assessed in survivors of cardiac arrest following targeted management regimens with goal temperatures of either 33°C or 36°C. Using a cohort of 455 survivors enrolled in the targeted temperature management trial,2 it was concluded that no significant difference was found in measures of cognitive performance between the 2 groups.

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Correspondence

June 1, 2015
Tobias Cronberg, MD, PhD; Gisela Lilja, OT; Janneke Horn, MD, PhD; Jesper Kjaergaard, MD, DMSci; Matt P. Wise, MD, DPhil; Tommaso Pellis, MD; Jan Hovdenes, MD, PhD; Yvan Gasche, MD, PhD; Anders Åneman, MD, PhD; Pascal Stammet, MD; David Erlinge, MD, PhD; Hans Friberg, MD, PhD; Christian Hassager, MD, DMSci; Michael Kuiper, MD, PhD; Michael Wanscher, MD, PhD; Frank Bosch, MD, PhD; Julius Cranshaw, MD, PhD; Gian-Reto Kleger, MD; Stefan Persson, MD; Johan Undén, MD, PhD; Andrew Walden, MD, PhD; Per Winkel, MD, DMSci; Jørn Wetterslev, MD, PhD; Niklas Nielsen, MD, PhD; for the TTM Trial Investigators
1Department of Neurology and Rehabilitation Medicine, Skåne University Hospital, Lund, Sweden2Department of Clinical Sciences, Lund University, Lund, Sweden
3Department of Intensive Care, Academic Medical Center, Amsterdam, the Netherlands
4Department of Cardiology, The Heart Centre, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
5Adult Critical Care, University Hospital of Wales, Cardiff, United Kingdom
6Intensive Care Unit, Santa Maria degli Angeli, Pordenone, Italy
7Department of Anesthesiology, Oslo University Hospital, Rikshospitalet, Oslo, Norway
8Department of Anesthesiology, Pharmacology and Intensive Care, Geneva University Hospital, Geneva, Switzerland
9Department of Intensive Care, Liverpool Hospital, Sydney, New South Wales, Australia
10Department of Anesthesiology and Intensive Care, Centre Hospitalier de Luxembourg, Luxembourg
2Department of Clinical Sciences, Lund University, Lund, Sweden11Department of Cardiology, Lund University, Lund, Sweden
2Department of Clinical Sciences, Lund University, Lund, Sweden12Department of Intensive and Perioperative Care, Skåne University Hospital, Lund, Sweden
3Department of Intensive Care, Academic Medical Center, Amsterdam, the Netherlands13Department of Intensive Care, Medical Center Leeuwarden, Leeuwarden, the Netherlands
14Department of Cardiothoracic Anesthesiology, The Heart Centre, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
15Department of Intensive Care, Rijnstaate Hospital, Arnhem, the Netherlands
16Department of Intensive Care, Royal Bournemouth Hospital, Bournemouth, United Kingdom
17Department of Intensive Care, Kantonsspital, St Gallen, Switzerland
18Departement of Anesthesia and Intensive Care, Örebro University Hospital, Örebro, Sweden
19Department of Intensive and Perioperative Care, Skåne University Hospital, Malmö, Sweden
20Department of Intensive Care, Royal Berkshire Hospital, Reading, United Kingdom
21Copenhagen Trial Unit, Centre of Clinical Intervention Research, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
2Department of Clinical Sciences, Lund University, Lund, Sweden22Department of Anesthesiology and Intensive Care, Helsingborg Hospital, Helsingborg, Sweden
JAMA Neurol. 2015;72(6):634-641. doi:10.1001/jamaneurol.2015.0169.
September 1, 2015
Niklas Nielsen, MD, PhD; Matt P. Wise, MD, DPhil; Tobias Cronberg, MD, PhD
1Department of Anesthesiology and Intensive Care, Helsingborg Hospital, Helsingborg, Sweden2Department of Clinical Sciences, Lund University, Lund, Sweden
3Adult Critical Care, Cardiff University Hospital, Cardiff, United Kingdom
2Department of Clinical Sciences, Lund University, Lund, Sweden4Department of Neurology and Rehabilitation Medicine, Skane University Hospital, Lund, Sweden
JAMA Neurol. 2015;72(9):1076-1077. doi:10.1001/jamaneurol.2015.1380.
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