Study concept and design: Hajjar.
Acquisition, analysis, or interpretation of data: Both authors.
Drafting of the manuscript: Hajjar.
Critical revision of the manuscript for important intellectual content: Both authors.
Statistical analysis: Hajjar.
Obtained funding: Hajjar.
Conflict of Interest Disclosures: The Alzheimer’s Disease Neuroimaging Initiative is funded by contributions from the following: Araclon Biotech, BioClinica Inc, Biogen Idec Inc, Bristol-Myers Squibb Co, Eisai Inc, Elan Pharmaceuticals Inc, Eli Lilly and Co, EuroImmun, F Hoffmann–La Roche Ltd and its affiliated company Genentech Inc, Fujirebio, GE Healthcare, IXICO Ltd, Janssen Alzheimer Immunotherapy Research & Development LLC, Johnson & Johnson Pharmaceutical Research & Development LLC, Medpace Inc, Merck & Co Inc, Meso Scale Diagnostics LLC, NeuroRx Research, Neurotrack Technologies, Novartis Pharmaceuticals Corp, Pfizer Inc, Piramal Imaging, Servier, Synarc Inc, and Takeda Pharmaceutical Co. No other disclosures were reported.
Funding/Support: Dr Hajjar is funded by the National Institute on Aging (R01AG042127) and Dr Levey is funded by the Emory Alzheimer’s Disease Research Center (P50 AG025688). The Alzheimer’s Disease Neuroimaging Initiative is funded by the National Institute on Aging, the National Institute of Biomedical Imaging and Bioengineering, the Alzheimer’s Association, and the Alzheimer’s Drug Discovery Foundation. The Canadian Institutes of Health Research provides funding to support Alzheimer’s Disease Neuroimaging Initiative clinical sites in Canada. Private sector contributions are facilitated by the Foundation for the National Institutes of Health (http://www.fnih.org). The grantee organization is the Northern California Institute for Research and Education, and the study is coordinated by the Alzheimer’s Disease Cooperative Study at the University of California, San Diego. Alzheimer’s Disease Neuroimaging Initiative data are disseminated by the Laboratory for Neuro Imaging at the University of Southern California.
Role of the Funder/Sponsor: The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.