Study concept and design: Payne, Chinnery.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Payne, Chinnery.
Critical revision of the manuscript for important intellectual content: All authors.
Obtained funding: Payne, Taylor, Chinnery.
Administrative, technical, or material support: Taylor.
Study supervision: Payne, Chinnery.
Conflict of Interest Disclosures: None reported.
Funding/Support: Dr Payne was funded by the Medical Research Council (United Kingdom). Dr Taylor receives support from the Wellcome Trust Centre for Mitochondrial Research (096919Z/11/Z), the Medical Research Council (United Kingdom) Centre for Translational Muscle Disease Research (G0601943) and the UK National Health Service Highly Specialised Rare Mitochondrial Disorders of Adults and Children Service. Dr Chinnery receives support from the Wellcome Trust (101876/Z/13/Z and 096919Z/11/Z), the Medical Research Council (United Kingdom) Centre for Translational Muscle Disease Research (G0601943), European Union FP7 Treat Iron-Related Childhood-Onset Neurodegeneration, and the National Institute for Health Research Newcastle Biomedical Research Centre based at Newcastle-upon-Tyne Hospitals National Health Service Foundation Trust and Newcastle University.
Role of the Funder/Sponsor: The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.