Accepted for Publication: February 10, 2015.
Published Online: April 6, 2015. doi:10.1001/jamaneurol.2015.0169.
Study concept and design: Cronberg, Lilja, Horn, Kjaergaard, Wise, Pellis, Hovdenes, Gasche, Åneman, Stammet, Erlinge, Friberg, Hassager, Kuiper, Wanscher, Wetterslev, Nielsen.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Cronberg, Lilja, Horn, Nielsen.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Cronberg, Lilja, Winkel, Wetterslev, Nielsen.
Obtained funding: Cronberg, Erlinge, Friberg, Wanscher, Nielsen.
Administrative, technical, or material support: Cronberg, Lilja, Nielsen.
Study supervision: Cronberg, Lilja, Horn, Kjaergaard, Wise, Pellis, Hovdenes, Gasche, Åneman, Stammet, Erlinge, Friberg, Hassager, Kuiper, Wanscher, Bosch, Cranshaw, Kleger, Persson, Undén, Walden, Wetterslev, Nielsen.
Conflict of Interest Disclosures: Dr Erlinge reported receiving speaker fees from Philips and Zoll. Drs Friberg, Nielsen, Pellis, and Wise reported receiving lecture fees from Bard Medical. No other disclosures were reported.
Funding/Support: The TTM trial was funded by independent research grants from the following nonprofit or governmental agencies: grants 20090275 and 20120491 from the Swedish Heart Lung Foundation, grant 100001 from the Arbetsmarknadens Försäkringsaktiebolag Insurance Foundation, grant 2013-3572 from the Swedish Research Council, regional research support, grants 134281 and 286321 from Region Skåne, grants 209851, 295281, 296211, and 353301 from governmental funding of clinical research within the Swedish National Health Services, Thelma Zoega Foundation, Krapperup Foundation, Thure Carlsson Foundation, Hans-Gabriel and Alice Trolle-Wachtmeister Foundation for Medical Research, Skåne University Hospital (all from Sweden), grant 7-12-0454 from TrygFonden (Denmark), and the European Clinical Research Infrastructures Network.
Role of the Funder/Sponsor: The funding sources had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and the decision to submit the manuscript for publication.
Group Information: The TTM Investigators are listed in Supplement 1.
Correction: This article was corrected on June 8, 2015, to fix a typo in the Group Information.