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Comment & Response |

Validation of the Association Between Neurologic Improvement With Decline in Blood Pressure and Recanalization in Stroke

Leonard L. L. Yeo, MBBS, MRCP1; Yao F. Chong, MBBS1; Vijay K. Sharma, MBBS1
[+] Author Affiliations
1Division of Neurology, Department of Medicine, National University Health System, Singapore
JAMA Neurol. 2015;72(4):477. doi:10.1001/jamaneurol.2014.4705.
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To the Editor We read with interest the study by Nagaraja et al1 regarding their observation about the relationship between neurologic improvement with decline in blood pressure and recanalization in acute ischemic stroke. Of various postulated mechanisms for this phenomenon, arterial recanalization was deemed to be the most plausible. However, the relationship between arterial recanalization and reduction in blood pressure remains poorly understood.


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April 1, 2015
Nandakumar Nagaraja, MD, MS; Harold P. Adams Jr, MD; José G. Merino, MD
1Stroke Diagnostics and Therapeutics Section, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland2University of Iowa, Iowa City
2University of Iowa, Iowa City
3Johns Hopkins Community Physicians, Bethesda, Maryland
JAMA Neurol. 2015;72(4):477-478. doi:10.1001/jamaneurol.2014.4690.
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