Accepted for Publication: October 29, 2014.
Published Online: February 16, 2015. doi:10.1001/jamaneurol.2014.3953.
Study concept and design: All authors.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: All authors.
Critical revision of the manuscript for important intellectual content: All authors.
Obtained funding: All authors.
Administrative, technical, or material support: Pérez-Otaño.
Study supervision: All authors.
Conflict of Interest Disclosures: None reported.
Funding/Support: This study was funded by the Unión Temporal de Empresas project at the Centro de Investigación Médica Aplicada, the Hereditary Disease Foundation (Dr Pérez-Otaño), and grants CSD2008-00005 (Dr Pérez-Otaño), BFU2009-1216 (Dr Wesseling), SAF2010-20636 (Dr Pérez-Otaño), and SAF2013-48983R (Drs Pérez-Otaño and Wessling) from the Spanish Ministry of Science.
Role of the Funder/Sponsor: The funding sources had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and the decision to submit the manuscript for publication.
Additional Contributions: Julio Artieda, MD, and José Obeso, MD (University Clinic and Medical School, University of Navarra, Pamplona, Spain), provided critical readings of the manuscript. The contributors did not receive financial compensation.