Accepted for Publication: August 22, 2014.
Published Online: November 10, 2014. doi:10.1001/jamaneurol.2014.2940.
Study concept and design: Nicholson, Kiernan, Vucic.
Acquisition, analysis, or interpretation of data: Geevasinga, Menon, Howells, Kiernan, Vucic.
Drafting of the manuscript: Geevasinga, Menon, Howells, Kiernan, Vucic.
Critical revision of the manuscript for important intellectual content: Nicholson, Kiernan, Vucic.
Statistical analysis: Geevasinga, Menon, Vucic.
Obtained funding: Kiernan, Vucic.
Administrative, technical, or material support: Geevasinga, Menon, Howells, Vucic.
Study supervision: Nicholson, Kiernan, Vucic.
Conflict of Interest Disclosures: None reported.
Funding/Support: This study was supported in part by research grants from the Motor Neuron Disease Research Institute of Australia (Dr Geevasinga) and the National Health and Medical Research Council of Australia (project grants 510233, 1024915, and 1055778; Drs Kiernan and Vucic). This work was also supported by funding to Forefront, a collaborative research group dedicated to the study of frontotemporal dementia and motor neuron disease, from the National Health and Medical Research Council of Australia (program grant 1037746, Dr Kiernan) and Pfizer Neuroscience (grant WS2343874, Dr Geevasinga).
Role of the Funder/Sponsor: The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.