Accepted for Publication: April 23, 2014.
Published Online: October 6, 2014. doi:10.1001/jamaneurol.2014.1326.
Study concept and design: Aquino, Lang.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Aquino.
Critical revision of the manuscript for important intellectual content: Mestre, Lang.
Study supervision: Lang.
Conflict of Interest Disclosures: Dr Lang has served as an advisor for Abbvie, Allon Therapeutics, Avanir Pharmaceuticals, Biogen Idec, Boerhinger-Ingelheim, Ceregene, Medtronic, Merck, Novartis, NeuroPhage Pharmaceuticals, Teva, and UCB. Dr Lang has received publishing royalties from Saunders, Wiley-Blackwell, Johns Hopkins Press, and Cambridge University Press and has served as an expert witness in cases related to the welding industry. No other disclosures were reported.
Funding/Support: Dr Aquino received a scholarship from CAPES Foundation, Brazil. Dr Lang has received grants from Brain Canada, Canadian Institutes of Health Research, Edmond J. Safra Foundation, Michael J. Fox Foundation, National Parkinson Foundation, Parkinson Society Canada, Tourette Syndrome Association, and W. Garfield Weston Foundation.
Role of the Funder/Sponsor: The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.