Accepted for Publication: May 15, 2014.
Published Online: August 18, 2014. doi:10.1001/jamaneurol.2014.1668.
Study concept and design: Marshall, Lu, Grossman, Ge.
Acquisition, analysis, or interpretation of data: Marshall, Lu, Brisset, Xu, Liu, Herbert, Ge.
Drafting of the manuscript: Marshall, Lu, Brisset, Xu, Liu, Herbert, Ge.
Critical revision of the manuscript for important intellectual content: Marshall, Lu, Grossman, Ge.
Statistical analysis: Marshall, Ge.
Obtained funding: Grossman, Ge.
Administrative, technical, or material support: Marshall, Ge.
Study supervision: Ge.
Conflict of Interest Disclosures: None reported.
Funding/Support: Dr Ge was supported by grants R01 NS076588 and R01 NS029029S1 from the National Institutes of Health and by research grant 4707A1 from the National MS Society. Dr Lu was supported by grants R01 MH084021, R01 NS067015, R01 AG042753, and R21 NS078656 from the National Institutes of Health. Dr Grossman was supported by grant R01 NS029029 from the National Institutes of Health.
Role of the Sponsor: The funding agencies had no role in the design and conduct of the study; collection, management, analysis, or interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Additional Contributions: We would like to thank Jacqueline Smith, Ilya Kister, MD, and Sanjeev Chawla, PhD, from the New York University School of Medicine for helping with data collection. We would also like to thank Danny J. Wang, PhD, from the David Geffen School of Medicine at the University of California, Los Angeles, for providing the pseudocontinuous ASL sequence. These individuals did not receive compensation from the funding sponsors.