Accepted for Publication: January 13, 2014.
Published Online: July 7, 2014. doi:10.1001/jamaneurol.2014.56.
Study concept and design: Domingo, Lee, Kaiser, Klein, Westenberger.
Acquisition, analysis, or interpretation of data: Domingo, Brüggemann, Freimann, Kaiser, Jamora, Rosales, Klein, Westenberger.
Drafting of the manuscript: Domingo, Westenberger.
Critical revision of the manuscript for important intellectual content: Lee, Brüggemann, Freimann, Kaiser, Jamora, Rosales, Klein.
Statistical analysis: Domingo, Brüggemann, Freimann, Kaiser.
Obtained funding: Klein, Westenberger.
Administrative, technical, or material support: Lee, Kaiser, Klein, Westenberger.
Study supervision: Lee, Jamora, Rosales, Klein, Westenberger.
Conflict of Interest Disclosures: Dr Domingo has received travel grants from the Movement Disorders Society and the German Neurological Society (DGN-Felgenhauer Foundation). Ms Freimann has received travel grants from the Movement Disorders Society and Seahorse Bioscience. She receives a PhD student salary from the University of Lübeck, Germany. Dr Jamora has received speakers’ honoraria and travel grants from GlaxoSmithKline, Abbott, Lundbeck, Torrent Pharma, and Boehringer-Ingelheim (local). Dr Rosales has consultancy positions with, and has received speakers’ honoraria from, Ipsen (international), Pfizer (international, regional, and local), GlaxoSmithKline, Abbott, and Novartis (local). Dr Klein does consultancy work with Centogene and has received speakers’ honoraria from Shire and Merz Pharma. No other disclosures were reported.
Funding/Support: This study was supported by the Jake’s Ride for Dystonia research grant through the Bachmann-Strauss Dystonia and Parkinson Foundation. Dr Domingo receives a scholarship from the German Academic Exchange Service (DAAD). Dr Brüggemann is supported by the German Research Foundation (DFG). Dr Kaiser is the recipient of a German Research Foundation grant (DFG LO 1555/3-2) for his studies on identification of targets and interactors of the DYT6-related THAP1 and the TARGET-CdLS-E-RARE joint transnational European Research Project on Rare Diseases Driven by Young Investigators. Dr Klein is the recipient of grants from the Herman and Lilly Schilling Foundation, the Bachmann-Strauss Dystonia and Parkinson Foundation, the DFG, and the Dystonia Medical Research Foundation. Dr Westenberger is supported by the Jake’s Ride for Dystonia research grant through the Bachmann-Strauss Dystonia and Parkinson Foundation and a research grant from the Fritz Thyssen Foundation. She is the recipient of a Habilitation Fellowship for Women Researchers, Habilitationsförderung fur Wissenschaftlerinnen, an intramural funding from the University of Lübeck, Germany.
Role of the Sponsor: The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.