Accepted for Publication: April 3, 2014.
Published Online: June 16, 2014. doi:10.1001/jamaneurol.2014.1011.
Study concept and design: Ariño, Saiz, Graus.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Ariño, Blanco, Dalmau, Saiz, Graus.
Critical revision of the manuscript for important intellectual content: All authors.
Obtained funding: Ariño, Dalmau, Graus.
Study supervision: Dalmau, Saiz, Graus.
Conflict of Interest Disclosures: Dr Dalmau reported receiving a research grant from Euroimmun and royalties from patents for the use of Ma2 and N-methyl-d-aspartate receptor as autoantibody tests. No other disclosures were reported.
Funding/Support: This work was supported by grants R01NS077851 and R01MH094741 from the US National Institutes of Health (Dr Dalmau), by grants 11/01780 (Dr Dalmau) and 12/00611 (Dr Graus) from the Spanish Fondo Investigaciones Sanitarias, and by Fundació la Marató TV3 (Dr Dalmau). Dr Ariño is supported by a postresidency grant from the Hospital Clinic, Barcelona, Spain, and Dr Martínez-Hernández is supported by grant CM12/00055 from Instituto Carlos III, Madrid, Spain.
Role of the Sponsor: The funding sources had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Additional Contributions: Mercedes Alba (Neuroimmunology Laboratory, Institut d’Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain) provided excellent technical support. We thank the physicians for the clinical information on their patients, and we thank the patients for their generous contribution to research.