Accepted for Publication: August 14, 2013.
Published Online: March 3, 2014. doi:10.1001/jamaneurol.2013.4786.
Study concept and design: Kruer.
Acquisition of data: All authors.
Analysis and interpretation of data: Kruer, Dalmau.
Drafting of the manuscript: Kruer.
Critical revision of the manuscript for important intellectual content: All authors.
Obtained funding: Woltjer, Dalmau.
Administrative, technical, and material support: Hoeftberger, Svoboda, Woltjer, Dalmau.
Conflict of Interest Disclosures: Dr Dalmau serves on the editorial board of Neurology; has a patent issued for the Ma2 autoantibody test (US 6,387,639; issued May 14, 2002); has a patent for the N-methyl-d-aspartate receptor autoantibody test (US 7,972,796 B2; issued July 5, 2011); has filed for patents for the GABAB receptor and LGI1 (leucine-rich, glioma inactivated 1) autoantibody tests; receives license fee payments for the N-methyl-d-aspartate receptor autoantibody test from Euroimmun; receives royalties from the patented Ma2 autoantibody test and the patented N-methyl-d-aspartate receptor autoantibody test; and has a patent application pending for the use of GABAB receptor and LGI1 as an autoantibody test. No other disclosures were reported.
Funding/Support: Dr Kruer is supported by grant K08NS083739 from the National Institute of Neurological Disorders and Stroke, the Sanford Health Foundation, the Sanford-Mayo Collaborative Fund, the Dystonia Medical Research Foundation, the Child Neurology Society, and the American Academy of Cerebral Palsy and Developmental Medicine. Dr Woltjer is supported by grant P30 AG008017 23 from the National Institute on Aging. Dr Dalmau is supported by Euroimmun, grants R01CA107192 and R01CA89054-06A2 from the National Institutes of Health, and the McKnight Foundation.
Role of the Sponsor: The funding organizations had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.