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Comment & Response |

Cerebral Venous Air Embolism—Reply

Daniel Lai, MD1; Ashutosh P. Jadhav, MD, PhD1
[+] Author Affiliations
1Department of Neurology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
JAMA Neurol. 2014;71(2):243-244. doi:10.1001/jamaneurol.2013.5556.
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In Reply We appreciate the insightful commentary from our colleagues, Schlimp et al, regarding our article on cerebral air embolism.1 Despite a lack of prospective data, emergent therapies focus on Trendelenburg patient positioning and hyperbaric oxygen treatment (HBOT). Moreover, the precise pathophysiology of cerebral venous air embolization has yet to be delineated. Nonetheless, the literature does provide a number of retrospective clinical observations and animal model studies on which we base our clinical decisions. Current therapies are relatively noninvasive, with low potential for major complications.


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February 1, 2014
Christoph J. Schlimp, MD; Pieter A. Bothma, FCA(SA), MMed; Andreas E. Brodbeck, MD
1Ludwig Boltzmann for Experimental and Clinical Traumatology, AUVA Research Centre, Vienna, Austria
2James Paget University Hospitals NHS Foundation Trust, Norfolk, England
JAMA Neurol. 2014;71(2):243. doi:10.1001/jamaneurol.2013.5414.
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