Accepted for Publication: November 18, 2013.
Published Online: January 6, 2014. doi:10.1001/jamaneurol.2013.5858.
Study concept and design: Olsson, Alfredsson.
Acquisition of data: All authors.
Analysis and interpretation of data: All authors.
Drafting of the manuscript: Hedström, Olsson.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Hedström, Alfredsson.
Obtained funding: Hillert, Olsson, Alfredsson.
Administrative, technical, and material support: Olsson.
Study supervision: Hillert, Olsson, Alfredsson.
Conflict of Interest Disclosures: Dr Hillert received honoraria for serving on advisory boards for Biogen Idec, Merck Serono, and Novartis and for speaker’s fees from Biogen Idec, Merck Serono, Bayer-Schering, Teva, and sanofi-aventis. He has served as principal investigator for and received projects supported by Biogen Idec, Merck Serono, and Bayer-Schering. His MS research is funded by the Swedish Research Council, the Bibbi and Nils Jensens Foundation, and the European Commission. Dr Olsson served on scientific advisory boards for Merck Serono, Biogen Idec, and sanofi-aventis; served as co-editor of Current Opinion in Immunology; received speaker honoraria from Novartis and Biogen; and receives research support from Bayer-Schering, sanofi-aventis, Biogen Idec, the Swedish Research Council (grant 07488), EU fp6 Neuropromise (grant LSHM-CT-2005-018637), EURATools (grant LSHG-CT-2005- 019015), the Söderberg Foundation, the Bibbi and Nils Jensens Foundation, the Montel Williams Foundation, and the Swedish Brain Foundation. Dr Alfredsson receives research support from the Swedish Medical Research Council (grant K2007-69X-14973-04-3) and Swedish Council for Working Life and Social Research (grant Dnr 2006-0655). No other disclosures were reported.
Funding/Support: The study was supported by grants from the Swedish Medical Research Council, the Swedish Council for Working Life and Social Research, the Knut and Alice Wallenberg Foundation, the AFA Foundation, the Swedish Brain Foundation, and the Swedish Association for Persons With Neurological Disabilities.
Role of the Sponsor: The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.